Epithelioid hemangioendothelioma (EHE) is a rare tumor of vascular origin. While it can be found in any tissue, it is most often found in lung and liver and usually has an intermediate behavior. EHEs originating from pleural tissue have been less frequently described than those from other sites. Furthermore, to date, all of the cited pleural EHEs were described as highly aggressive. In the pres...

A case of a rare epithelioid hemangioendothelioma (EHE) with multifocal location in a 32 year-old male is reported. The patient presented to our hospital with a knee pain. After thorough investigations and establishing the diagnosis, surgical treatment was done. This tumor involves bones of the axial skeleton and long tubular bones. EHE is usually multifocal in more than 50% of the cases. The m...

Epithelioid haemangioendothelioma (EHE) is a rare tumour of endothelial cell origin that arises from soft tissue, liver, lungs and rarely, the brain. We present a case of cerebral EHE in a 43 year old previously well female, who suffered two generalised tonic-clonic seizures. Contrast enhanced CT and MRI brain showed a left frontal lobe vividly enhancing intra-axial lesion at the grey-white jun...

Kaposiform hemangioendothelioma is an aggressive endothelial-derived spindle cell neoplasm that occurs nearly exclusively during childhood and teenage years. The lesion grows rapidly and is often associated with Kasabach-Merritt syndrome.In this study a 24 days old male neonate who presented with an ill-defined deeply situated violaceous mass on his left arm is described. He had also anemia and...

Kaposiform hemangioendothelioma is an aggressive endothelial-derived spindle cell neoplasm that occurs nearly exclusively during childhood and teenage years. The lesion grows rapidly and is often associated with Kasabach-Merritt syndrome. In this study a 24 days old male neonate who presented with an ill-defined deeply situated violaceous mass on his left arm is described. He had also anemia an...

Interstitial deletions of the long arm of chromosome 13 (13q) are related with variable phenotypes, according to the size and the location of the deleted region. The main clinical features are moderate/severe mental and growth retardation, cranio-facial dysmorphism, variable congenital defects and increased susceptibility to tumors. Here we report a 3-year-old girl carrying a de novo 13q13.3-21...

26 Background. Epithelioid hemangioendothelioma is a rare vascular tumor of borderline or 27 low-grade malignancy. The lungs and liver are the two common primary organs affected. 28 Metastatic disease was reported in more than 100 cases in the literature. However, no firm 29 conclusions can be determined for recommended treatment options. 30 Case presentation. The current case presents a patien...

Hemangioendothelioma is borderline or intermediate type of vascular neoplasm. Hemangioendothelioma is rare lesion that constitutes less than 0.5% of the malignant tumors of bone. We present a case of low-grade hemagioendothelioma of the skull in a 29-yr-old woman. She had pain, diplopia and exophthalmos of the left eye. Radiographic images showed a relatively well-demarcated, expansile osteolyt...

Epithelioid hemangioendothelioma is an uncommon vascular tumor of intermediate malignant potential. Hepatic epithelioid hemangioendothelioma (HEHE), a rare sarcoma of the liver, usually appears as multiple nodules involving both hepatic lobes, and can be misdiagnosed as metastatic carcinoma on the basis of its radiologic manifestations. HEHE is composed of neoplastic endothelial cells that clos...