نتایج جستجو برای: hematologic
تعداد نتایج: 21490 فیلتر نتایج به سال:
how to cite this article: arzanian mt, shamsian bsh, karimzadeh p, kajiyazdi m, malek f, hammoud m. posterior reversible encephalopathy syndrome in pediatric hematologic-oncologic disease: literature review and case presentation. iran j child neurol. 2014 spring 8(2):1-10. objective posterior reversible encephalopathy syndrome (pres) is a cliniconeuroradiological disease entity, which is repres...
The transforming growth factor(TGF) signaling pathway is an essential regulator of cellular processes, including proliferation, differentiation, migration, and cell survival. During hematopoiesis, the TGFsignaling pathway is a potent negative regulator of proliferation while stimulating differentiation and apoptosis when appropriate. In hematologic malignancies, including leukemias, myeloprolif...
OBJECTIVE To assess the frequency of hematologic malignancies at diagnosis and to determine the incidence and predictors of malignant transformation during follow-up in patients with polyneuropathy associated with monoclonal gammopathy. METHODS Potential predictors of malignant transformation from medical history, hematologic, neurologic, and laboratory examination performed each 6 months wer...
BACKGROUND Infants with Down syndrome are at increased risk for hematologic abnormalities, including leukemoid reaction, transient myeloproliferative disorder, and congenital leukemia. The differential diagnosis of a vesiculopustular eruption in an infant with Down syndrome and these hematologic abnormalities is broad and includes benign, self-limited disorders as well as life-threatening infec...
Imatinib and recombinant interferon alpha (rIFNalpha) can induce remission in polycythemia vera (PV) patients, but gauging the depth of responses has not been possible due to lack of a specific disease marker. We found that patients undergoing imatinib (n = 14) or rIFNalpha (n = 7) therapy remained strongly positive for V617F JAK2, although there was a significant reduction in the median percen...
Hepatitis C virus (HCV) has been associated with the development of B-cell non-Hodgkin lymphomas. We recently reported the regression of splenic lymphoma with villous lymphocytes (SLVL) in patients with HCV after antiviral treatment, demonstrating a direct role of HCV in lymphomagenesis. This study expands our previous results in 18 patients with chronic HCV and SLVL. Mixed cryoglobulinemia (MC...
There are literally dozens of distinct lymphoma subtypes, each with its own unique molecular and clinical features. Although systemic cytotoxic and targeted therapies have improved dramatically, radiation therapy remains an important modality for optimal clinical outcomes. With contributions from nationally recognized experts, Hematologic Malignancies offers an overview of the full spectrum of ...
Urine polyamine:creatinine ratios (nm per mg) measured in eight children with active hematologic cancers were compared with those of age-matched controls and children with hematologic cancer in remission. Polyamine:creatinine ratios in the children with active disease were significantly higher than those of the controls (p less than 0.0025) and of the children in remission (p less than 0.0025)....
We studied several factors that may influence the duration of hematologic recovery to reach neutrophil counts (>0.5 and 1.5×109/L) and thus, indirectly, the prognosis in 91 patients with well-established drug-induced agranulocytosis. Multivariable analysis showed that neutrophil count <0.1×109/L and infection profile (severe infections or septic shock) adversely influenced the neutrophil recove...
There are literally dozens of distinct lymphoma subtypes, each with its own unique molecular and clinical features. Although systemic cytotoxic and targeted therapies have improved dramatically, radiation therapy remains an important modality for optimal clinical outcomes. With contributions from nationally recognized experts, Hematologic Malignancies offers an overview of the full spectrum of ...
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