Hematological malignancies treatment improved over the last years resulting in increased achievement of complete or partial remission, but unfortunately high relapse rates are still observed. Therefore, sustainment of long-term remission is crucial. Immune system has a key role in tumor surveillance. Natural killer (NK) cells, at the frontier of innate and adaptive immune system, have a central...

Fusidic acid is an active agent against a wide variety of gram-positive bacteria, and it has been increasingly used in methicillin-resistant Staphylococcus aureus infection. The major adverse effects are mild gastrointestinal discomfort and diarrhea. The hematological side effects such as granulocytopenia and thrombocytopenia have been rarely reported in western countries, but have not been doc...

Background: Hematological abnormalities are a common complication of HIV infection and occur in all stages of the infection. These abnormalities increase as the disease advances. We aimed to evaluate the diagnostic utility of bone marrow sampling in HIV-positive patients. Methods: 40 HIV-infected individuals were screened for hematological abnormalities. Investigations such as iron studies, he...

septicemia in neonates is the commonest cause of mortality. early recognition and diagnosis of neonatal sepsis remains a challenge because of the variable and nonspecific clinical presentation. the laboratory criteria are often non specific and not fully reliable. the objective of this review is to highlight the various hematological and biological markers of neonatal sepsis. we searched pubmed...

introduction: fasting during ramadan is a religious obligation for healthy adult muslims. this study aimed to investigate the effects of ramadan fasting and physical activity on blood hematological and biochemical parameters in male and female subjects. methods: in this study, 50 healthy subjects were randomly assigned to four groups: male control fasting (mcf) group (n=13), male training fasti...

abstract background malaria is an acute and chronic illness characterized by paroxysms of fever, chills, sweating, fatigue, anemia, and splenomegaly. most malarial deaths occur in infants and young children.anemia in malaria has diverse pathophysiologic mechanisms such as direct invasion of red cells, in the following, we presented comparison of hematological aspects: children with malaria and ...

BACKGROUND Improvements in antimetabolite drugs have prolonged the survival of patient with hematological malignancies. However, these drugs may have hepatotoxic side effects and may induce acute liver failure, chronic liver fibrosis, cirrhosis, or even hepatocellular carcinoma (HCC). Although liver resection remains a curative option for HCC, its role in HCC with hematological malignancies has...

background: interferon beta-la and -1b have been increasingly used for the treatment of multiple sclerosis (ms). the most frequent systemic adverse effects are flu-like symptoms. laboratory abnormalities include asymptomatic leukopenia and elevated hepatic transaminases. myelodysplastic syndrome (mds) refers to a spectrum of hematological disorders which can occur in different situations. sever...

Background: Early detection of neonatal sepsis and categorization of patients based on clinical severity is not yet effectively achieved. Some hematological parameters are used to formulate a hematological scoring system (HSS) and a modified hematological scoring system (MHSS) to diagnose neonatal sepsis. A promising biomarker: Presepsin, or Soluble Cluster of Differentiation 14 SubType (sCD14-...