Beta-thalassemia (β-thal) is a congenital hemoglobinopathy explained by a decreased level (β+) or absence (βο) of β-globin gene expression. Microcytic hypochromic anemia and various clinical symptoms comprising severe anemia to clinically nonsymptomatic features. Treatment with an ordered blood transfusion and iron chelator agents can decrease transfusion iron overload that causes normal matura...

We report the case of a 35-year-old Tunisian women with a chronic anemia non investigated for a long time. Laboratory analysis using advanced technology of DNA sequencing revealed a compound heterozygote for Hb O Arab and cd 39 beta degrees-thalassemia. It's the first time that such a genotype has been characterized by gene sequencing.

Rationale and Objectives: Hemoglobinopathies are among the most commonly inherited genetic disorders in humans considered as a major public health problem Saudi Arabia. The prevalence of hemoglobinopathies is severe threat to society future generations if assessment pre-marriage cohorts not monitored. purpose this study analyze type relation age, gender mutations assess cohort. Materials Method...

Sickle cell disease is an inherited hemoglobinopathy. The patients with sickle had a small life years, before the advancement of medical science and development newer drugs. These have improved expectancy among patients. Females are reaching reproductive age expectant becoming mothers. But pregnancy in carries major fetal maternal complications. Managing from conception to delivery difficult ta...