نتایج جستجو برای: hemorrhagic transformation

تعداد نتایج: 244894  

Journal: :Stroke 2002
Chelsea S Kidwell Jeffrey L Saver Joaquin Carneado James Sayre Sidney Starkman Gary Duckwiler Y Pierre Gobin Reza Jahan Paul Vespa J Pablo Villablanca David S Liebeskind Fernando Vinuela

BACKGROUND AND PURPOSE Hemorrhagic transformation (HT) is a major complication of intra-arterial (IA) thrombolytic therapy. Identifying significant predictors of hemorrhage after thrombolysis would be useful in guiding patient selection for IA treatment. METHODS Data were collected retrospectively on consecutive patients with acute focal cerebral ischemia within the anterior or posterior circ...

Journal: :Stroke 2013
Nawaf Yassi Mark W Parsons Søren Christensen Gagan Sharma Andrew Bivard Geoffrey A Donnan Christopher R Levi Patricia M Desmond Stephen M Davis Bruce C V Campbell

BACKGROUND AND PURPOSE Intracerebral hemorrhage is a serious potential complication of stroke thrombolysis. We investigated the optimal computed tomography perfusion (CTP) parameter to predict cerebral parenchymal hematoma (PH) in acute ischemic stroke. METHODS Patients with hyperacute ischemic stroke had whole-brain CTP and follow-up computed tomography/MRI to identify hemorrhagic transforma...

Journal: :Acta neurologica Taiwanica 2009
Cheung-Ter Ong Yu-Hsiang Su Sheng-Feng Sung Chi-Shun Wu Yung-Chu Hsu

OBJECTIVE To discuss the ethical challenge in thrombolytic therapy. BACKGROUND Thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-Pa) has been found to be beneficial to the outcome of patients who had a stroke. However, the ethic issue that is related to intravenous rt-Pa infusion has not been discussed. PATIENTS Four patients with a middle cerebral artery (MCA) inf...

Journal: :Stroke 2001
C Berger M Fiorelli T Steiner W R Schäbitz L Bozzao E Bluhmki W Hacke R von Kummer

BACKGROUND AND PURPOSE The term symptomatic hemorrhage secondary to ischemic stroke implies a clear causal relationship between clinical deterioration and hemorrhagic transformation (HT) regardless of the type of HT. The aim of this study was to assess which type of HT independently affects clinical outcome. METHODS We used the data set of the European Cooperative Acute Stroke Study (ECASS) I...

2017
Zoe Wolcott Ayush Batra Matthew B. Bevers Cristina Sastre Jane Khoury Matthew Sperling Brett C. Meyer Kyle B. Walsh Opeolu Adeoye Joseph P. Broderick W. Taylor Kimberly

OBJECTIVE ST2 is a member of the toll-like receptor superfamily that can alter inflammatory signaling of helper T-cells. We investigated whether soluble ST2 (sST2) could independently predict outcome and hemorrhagic transformation (HT) in the setting of stroke. METHODS We measured sST2 in patients enrolled in the Specialized Program of Translational Research in Acute Stroke (SPOTRIAS) network...

Journal: :Circulation. Cardiovascular quality and outcomes 2013
Michael T Mullen Charles J Moomaw Kathleen Alwell Jane C Khoury Brett M Kissela Daniel Woo Matthew L Flaherty Pooja Khatri Opeolu Adeoye Simona Ferioli Dawn Kleindorfer

major objective of inpatient stroke care is the prevention of medical and neurological complications, although rare, hemorrhagic transformation (HT) of an isch-emic stroke (IS) can cause neurological deterioration and is associated with an increased risk of death. 1 If HT can be reliably identified in administrative data, it could become a component of hospital quality benchmarks. Previous stud...

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