Vasculitis has protean manifestations with etiological non-specificity of histological lesions. The natural history of Henoch-Schönlein purpura in adults is less well established. We report an adult female patient who presented with palpable skin purpura and was evaluated to have IgA nephritis who remains stable on treatment with cyclophosphamide and steroids.

Henoch-Shönlein purpura (HSP) is an acute, self-limited, systemic, small vessel vasculitis, that induces skin lesions, arthritis and abdominal pain. Palpable purpura is the most common manifestation in pediatric patients with HSP. We present an atypical case of HSP in a young patient and report successful treatment of the atypical skin lesions, while avoiding surgery.

The clinico-pathological features of 133 consecutive cases of Henoch-Schönlein purpura are presented, with emphasis on the gastrointestinal manifestations. The potential pitfalls of contrast radiography are underlined with respect to management of intussusception and a plea is made to re-establish clinical assessment of the abdomen as the prime indicator in deciding to undertake laparotomy.

Received for publication 14 August 1981 and in revised form 16 November 1981. membranous GN, membranoproliferative GN types I and II, mesangial GN with IgA or C3 deposition and Henoch Sch6nlein's purpura. Loss of C3b receptor antigen in the diffuse proliferative nephritis of SLE distinguishes it both from nonproliferative lupus nephritis and other immunologically mediated proliferative GN.

the aim of this study was to investigate the possible influence of interferon-gamma (ifn- γ) gene polymorphism +874 (a/t) (rs2430561) in the susceptibility and renal complications of patients with henoch-schonlein purpura (hsp). we also studied the effects of ifn-γ allelic variation on serum levels of pro-and anti-inflammatory cytokines in hsp patients. the  study  population  comprised  97  pa...

Dr. J.-C. Davin, Service de Pédiatrie, Bât. 35, CHU Sart-Tilman, B-4000 Liège 1 (Belgium) Dear Sir, In 1988, we demonstrated an increased intestinal permeability to [51Cr]EDTA in some children presenting with idiopathic IgA nephropathy or with Henoch-Schönlein purpura nephritis [1]. Three further studies of intestinal permeability were reported in adult idiopathic IgA nephropathy [2-4]. Two [2,...

OBJECTIVES To describe a group of patients treated at our service for Henoch-Schönlein purpura, with emphasis on recurrent and chronic cases, and to compare clinical and demographic characteristics of patients with monocyclic and recurrent disease. METHODS Data on 67 patients who had been treated since disease onset were analyzed. Twelve patients were excluded because they failed to return fo...

An eight year old boy with Henoch-Schonlein Purpura (HSP) presented with acute compartment syndrome (ACS) of his left hand following arterial cannulation of his radial artery in intensive care unit. Emergency decompression and fasciotomy were performed. The authors report this first case in literature and discuss how HSP can be complicated by ACS and ways to prevent the latter from happening.

The burden of Crohn’s disease and ulcerative colitis is substantially increased by extraintestinal manifestations (EIMs). In addition to EIMs, there is very rare occurrence of autoimmunopathies like Henoch-Schönlein purpura (HSP) in inflammatory bowel disease. HSP is an inflammatory disease damaging small vessels by immune complex depositions, and affects the skin, joint, kidneys and gastrointe...