Hepatocerebral MPV17-MDS is quite rare (<30 confirmed cases), with limited findings described on MR imaging. We report 2 siblings having abnormalities within the reticular formation of the lower brain stem and within the reticulospinal tracts at the cervicocranial junction on T2WI. The presence of these MR imaging findings (relative to previous reports) raises the possibility that they represen...

The moduli spaceM0,n plays important roles in algebraic geometry and theoretical physics. Yet, some basic properties of M 0,n still remain open. For example, M0,n is rational and nearly toric (that is, it contains a toric variety as a Zariski open subset), but it is not a toric variety itself starting from dimension 2 (n ≥ 5). So, a basic question is: Can it be degenerated flatly to a projectiv...

Wilson's disease (WD) is not as rare as once believed, and has a wide range of presentations with equally wide range of age of onset. Sometimes the primary presentation might be unusual and may require a thorough investigation to avoid a misdiagnosis. Our case presented with uncontrolled seizures, severe hypokalemia, renal failure, and hypoparathyroidism. After being diagnosed as WD and treated...

Wilson disease is associated with multisystem involvement. We describe a patient of Wilson disease with severe arthropathy, which completely reversed following liver transplantation. This is the first case report in literature describing the complete reversal of Wilson disease related arthropathy by liver transplantation.

1. K. R. L. Hall, Curr. Anthropol. 4, 479 (1963). 2. Specific examples of tool use by birds: A. Alcock, Ibid 112, 542 (1970); A. H. Chisholm, ibid. 96, 380 (1954); D. Lack, Sci. Amer. 188, 66 (April 1953); H. B. Lovell, Wilson Bull. 70, 280 (1957); G. C. Milliken and R. I. Bowman, Living Bird 6, 23 (1967); J. van Lawick-Goodall Nature 212, 1468 (1966); and H. van Lawick, Nat. Geogr. Mag. 133, 6...

In its earliest clinical phase, Alzheimer's disease characteristically produces a remarkably pure impairment of memory. Mounting evidence suggests that this syndrome begins with subtle alterations of hippocampal synaptic efficacy prior to frank neuronal degeneration, and that the synaptic dysfunction is caused by diffusible oligomeric assemblies of the amyloid beta protein.

Wilson disease (WD), known as hepatolenticular degeneration (HLD), is a treatable autosomal recessive disorder of copper metabolism. Because deposits in the liver first, not only original defective organ but also most affected organ. The injury one main causes death throughout course disease. Therefore, treatment task WD treatment, which great significance to improve prognosis patients. Autopha...

Wilson's disease is known for its protean manifestations due to abnormal copper metabolism. Although liver, brain and eyes are the well established sites for the latter but it can be speculated for other organs too. We report a case of Wilson's disease with tricuspid regurgitation possibly due to abnormal deposition of copper in heart.

BACKGROUND Frontotemporal lobar degeneration (FTLD) is responsible for as many as every fifth case of early-onset dementia. Very few epidemiological studies of FTLD have been conducted; there are no published epidemiological data of FTLD from Finland or the other Nordic countries. The C9ORF72 expansion-associated FTLD is common in Finland; thus, the prevalence of FTLD is expected to be high in ...