نتایج جستجو برای: hepatorenal
تعداد نتایج: 1134 فیلتر نتایج به سال:
The present study aimed to investigate the beneficial effects of the treatment with extracts from the edible mushroom Lactarius deterrimus (Ld) and the chestnut Castanea sativa (Cs), separately and in combination (MIX Ld/Cs), on oxidative stress and advanced glycation end-product (AGE)-mediated hepatorenal injury in a rat model of streptozotocin (STZ)-induced diabetes by examining pathways resp...
A change in hepatic blood flow caused by the hepatic arterial buffer response (HABR) occurs as fatty liver disease progress. The aim of this longitudinal cohort study was to investigate whether fatty liver with the HABR induces metabolic disorders. In 2009 and 2010, 494 (89.5%) participants were enrolled. The median follow-up duration was 5.0 (interquartile range, 3.9-6.0) years. The hazard rat...
There is a need to reassess the application of MELD and the impact of renal insufficiency with consideration for developing an algorithm with exception points that would lead to timely allocation of livers to patients with hepatorenal syndrome prior to occurrence of permanent renal damage without jeopardizing post-transplant survival.
BACKGROUND & AIMS An earlier pilot study from our liver unit suggested benefit from treatment with pentoxifylline (PTX), an inhibitor of tumor necrosis factor (TNF), in severe acute alcoholic hepatitis. The aim of the present study was to evaluate this treatment in a larger cohort of patients. METHODS One hundred one patients with severe alcoholic hepatitis (Maddrey discriminant factor > or =...
Acetaminophen (paracetamol, APAP) has a worldwide usage. Nevertheless, overdosing may induce severe toxicity. Dexpanthenol (DXP) is the alcohol provitamin form of vitamin B5 with antiinflammatory and antioxidant efficacy. In the present study, the biochemical and histological protective effects of DXP against acetaminophen-induced oxidative hepatorenal damage were examined. Rats were divided in...
BACKGROUND Chronic liver disease is becoming an increasingly frequent diagnosis for patients in the intensive care setting with such diagnoses as symptomatic ascites, spontaneous bacterial peritonitis, hepatorenal syndrome, or fulminant hepatic failure. OBJECTIVE To review frequent diagnoses for patients with chronic liver disease admitted to the intensive care unit and discuss current concep...
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