OBJECTIVE To obtain preliminary data on the effects of an auricular acupuncture protocol, Battlefield Acupuncture (BFA), on self-reported pain intensity in persons with chronic Spinal Cord Injury (SCI) and neuropathic pain. DESIGN Pilot randomized delayed entry single center crossover clinical trial at an outpatient rehabilitation and integrative medicine hospital center. METHODS Chronic (>...

OBJECTIVES To (1) determine the efficacy of venlafaxine XR for the treatment of pain (secondary aim) in individuals with spinal cord injury (SCI) enrolled in a randomized controlled trial (RCT) on the efficacy of venlafaxine XR for major depressive disorder (MDD) (primary aim); and (2) test the hypothesis that venlafaxine XR would be effective for both neuropathic and nociceptive pain. DESIGN...

conclusions coq10 abolished neuropathic pain in cci rats. prevention of cell loss might be attributed to the analgesic effect of coq10. hence, it might be used as a therapeutic intervention for neuropathic pain. background oxidative stress contributes to neuropathic pain. coenzyme q10 (coq10) is used for the treatment of neurodegenerative diseases. however, there is no report regarding the ther...

Neuropathic pain is a chronic condition representing a significant burden for patients, society, and healthcare systems. The prevalence of neuropathic pain in the general population has been estimated at 7-8% and is expected to increase in the future. Neuropathic pain differs from nociceptive pain and requires a different therapeutic approach; and the management of neuropathic pain is complicat...

UNLABELLED The Food and Drug Administration (FDA), Substance Abuse and Mental Health Services Administration (SAMHSA), and the National Institute for Drug Abuse (NIDA) report that no sound scientific studies support the medicinal use of cannabis. Despite this lack of scientific validation, many patients routinely use "medical marijuana," and in many cases this use is for pain related to nerve i...

In recent years we have witnessed the widespread use of herbal and traditional medicines. In many cases, people use traditional treatments arbitrarily and without consultation with a qualified person (1). As a teacher, I have frequently seen a number of my colleagues and others use herbal medicines and traditional methods for their medical problems. Looking at the papers published in this journ...

Growing evidence indicates that chronic neuropathic pain is frequently accompanied by an array of psychiatric diseases, such as depression and anxiety. Electroacupuncture (EA), as one therapy of traditional Chinese medicine, has displayed potent antidepressant-like effects in numerous clinical studies. The present study was designed to examine the possible effects of EA on the depressive and an...

BACKGROUND A large number of population-based studies of chronic pain have considered neuropathic sensory symptoms to be associated with a high level of pain intensity and negative affectivity. The present study examines the question of whether this association previously found in non-selected samples of chronic pain patients can also be found in chronic pain patients with underlying pathology ...

Today huge population worldwide is affected with the chronic debilitating neuropathic pain. A high level of dexterity is required for the diagnosis of neuropathic pain as it can develop gradually with time. Diagnosing and treating neuropathic pain is still a challenge to clinicians but if it is suspected, then various diagnostic screening tools such as neuropathic pain scale, Leeds assessment o...

UNLABELLED Neuropathic pain is characterized by persistent, intractable pain following damage or dysfunction of the nervous system. Analgesics that include central, rather than purely peripheral, targets are more effective when treating neuropathic pain, highlighting the spinal and/or supraspinal mechanisms that contribute to this aberrant pain condition. The striatum represents one of the brai...