Osler-Weber-Rendu disease (OWRD) or Hereditary Hemorrhagic Telangiectasia (HHT) is a rare autosomal dominant disorder that causes muco-cutanesous and visceral vascular dysplasia and results in increased tendency for bleeding [1-4]. Patients with HHT may present with variety of symptoms and management differs accordingly. Epistaxis is the most common symptom of HHT and mucocutaneous telangiectas...

OBJECTIVE Hereditary hemorrhagic telangiectasia is a genetic disorder characterized by visceral and mucocutaneous arteriovenous malformations (AVMs). Clinically indistinguishable hereditary hemorrhagic telangiectasia 1 and hereditary hemorrhagic telangiectasia 2 are caused by mutations in ENG and ALK1, respectively. In this study, we have compared the development of visceral and mucocutaneous A...

PURPOSE To describe the clinical and imaging features of seven patients with hereditary hemorrhagic telangiectasia and an exceptional number of cerebral arteriovenous malformations (AVMs). METHODS One hundred thirty-six patients from a dedicated hereditary hemorrhagic telangiectasia clinic were screened systematically for cerebral AVMs by means of MR imaging. Thirty-one were found to have abn...

Hereditary haemorrhagic telangiectasia is a rare disease. Hepatic involvement is infrequent. A patient with an extensive hepatic arteriovenous malformation is presented. Characteristic computed tomographic and angiographic findings are described followed by a review of the literature.

Dexfenfluramine associated pulmonary arterial hypertension occurring in a patient with hereditary haemorrhagic telangiectasia related to a mutation within the endoglin gene is described. This report highlights the critical role of the TGF-beta signalling pathway in this condition.

The need for higher performance electronics for space and defense applications has driven the development of InP heterojunction technologies. For the past 10 years, TRW has been developing InP HBT and HEMT technologies for mission critical applications [1– 3]. Consistent and continuous improvements in the basic MBE structure and process technology have enhanced device and circuit performance, p...

Laccase-mediator systems (LMS) have been widely studied for their capacity to oxidize the nonphenolic subunits of lignin (70-90% of the polymer). The phenolic subunits (10-30% of the polymer), which can also be oxidized without mediators, have received considerably less attention. Consequently, it remains unclear to what extent the presence of a mediator influences the reactions of the phenolic...

The freeze-out of hot and dense hadronic matter formed in relativistic nuclear collisions is probed by HBT interferometry of identical pions, kaons, etc. Coulomb repulsion/attraction of positive/negative particles show up at small particle momenta and is also very sensitive to the freeze-out conditions. The source sizes and times freeze-out are extracted from π/π spectra and HBT radii and compa...