± S.E.)6) was chromatographed on a silica gel colurnn to separate it into the 100% hexane, 20% AcOEtl hexane, 50% AcOEtlhexane and 100% AcOEt frs. The bioassay results clearly confirmed that the active component(s) in the original hexane fr. were concentrated in the 20% AcOEtfhexane fr. (92,4%± 1.6). The activities of the other frs. were as follows: 100% hexane fr. (O.O%± O.O), 50% AcOEt!hexane...

A detailed characterization of the microemulsion composition is necessary to make the phosphorimetry suitable as powerful analytical methodology. Four microemulsion systems (hexane/n-butanol/SDS/water, hexane/n-pentanol/SDS/water, hexane/3-pentanol/SDS/ water, and hexane/n-hexanol/SDS/water) were studied, establishing the oil/water (O/W) microemulsion composition with best phosphorimetric chara...

IN AN EARLIER STUDY (Barr et al., 1981) we explored the pathogenesis of soft-tissue necrosis induced in guinea-pigs by the concrolled extravascular administration of cytotoxic drugs. This system provides a model of the phenomenon which may complicate the inadvertent perivenous injection of cancer chemotherapeutic agents in clinical practice. The current investigation was undertaken in order to ...

Several species of Senna are well known for their therapeutic properties, being used in folk medicine to treat throat inflammation and constipation. In this regard, the anti-inflammatory, laxative and intestinal motility effects of different extracts of Senna macranthera (Colladon) H. Irwin and Barneby leaves were determined. The hexane extract significantly reduced carrageenan-induced paw oede...

The aim of this study was to measure permeation of the herbicide dichlobenil in Casoron 4G through disposable and chemically protective nitrile gloves using an American Society for Testing and Materials-type permeation cell and a closed-loop system employing two different solvents (hexane and water) and two different challenge situations (aqueous emulsion and solid formulation). Capillary gas c...

This paper describes results of a multiobjective comparative assessment of several established and emerging technologies for extraction of a natural antimalarial substance, artemisinin. Extractions by hexane, supercritical carbon dioxide, hydrofluorocarbon HFC-134a, ionic liquids, and ethanol were considered. Hexane extraction is an established technology and appears to be the most cost-effecti...

A variety of genes are involved in determining the level of organic solvent tolerance of Escherichia coli K-12. Gene ostA is one of the genes contributing to the level of organic solvent tolerance. This gene was cloned from an n-hexane-tolerant strain of E. coli, JA300. A JA300-based n-hexane-sensitive strain, OST4251, was converted to the n-hexane-tolerant phenotype by transformation with DNA ...

Hexane, chloroform and ethanol extracts of Malva parviflora L. and Malvastrum coromandelianum L. were tested for their antibacterial, antifungal and irritant activities. While the hexane, chloroform, ethanol and aqueous extracts along with the polar mass of Amaranthus viridis L. were tested for above activities, except that of the antifungal. The extracts of Malva parviflora L. and Malvastrum c...

Crude rhizome extracts and volatile oils of Curcuma aromatica were evaluated for chemical composition and anti-mosquito potential, including larvicidal, adulticidal, and repellent activities against the Aedes aegypti mosquito. Chemical identification achieved by GC/MS analysis revealed that xanthorrhizol, 1H-3a, 7-methanoazulene and curcumene at 35.08 and 13.65%, 21.81 and 30.02%, and 13.75 and...

Turmeric is an important spice crop with documented human health benefits associated with chemicals called curcuminoids. In this study, the termite Reticulitermes flavipes (Kollar) was exposed to different solvent extracts of turmeric to investigate potential termiticidal properties. Treating termites with hexane extracts of purified lab-grade curcuminoids had no effect on termites. However, in...