نتایج جستجو برای: high cell density culture

تعداد نتایج: 3901653  

Journal: :Investigative ophthalmology & visual science 1997
K J Strissel W B Rinehart M E Fini

PURPOSE Classic studies have demonstrated that corneal epithelial cell density in culture can alter the balance of stimulatory and inhibitory cytokines controlling the elaboration of collagenolytic activity by co-cultured stromal cells. The current study attempts to bring the understanding of this mechanism to a molecular level. METHODS A rabbit primary corneal cell culture model was used. ...

Journal: :iranian journal of basic medical sciences 0
sajad sahab negah histology and embryology group, basic science department, faculty of veterinary medicine, shiraz university, shiraz, iran shefa neuroscience research center, khatam alanbia hospital, tehran, iran hadi aligholi department of neuroscience, school of advanced medical sciences and technologies, shiraz university of medical sciences, shiraz, iran zabihollah khaksar histology and embryology group, basic science department, faculty of veterinary medicine, shiraz university, shiraz, iran hadi kazemi pediatric department, medical faculty, shahed university, tehran, iran sayed mostafa modarres mousavi shefa neuroscience research center, khatam alanbia hospital, tehran, iran

objective(s): in order to grow cells in a three-dimensional (3d) microenvironment, self-assembling peptides, such as puramatrix, have emerged with potential to mimic the extracellular matrix. the aim of the present study was to investigate the influence of the self-assembling peptide on the morphology, survival, proliferation rate, migration potential, and differentiation of human meningioma st...

F. Yekani, M. Azarnia M. Massumi T. Peirouvi

Hippocampal neural stem/progenitor cells (hipp-NS/PCs) of the adult mammalian brain are important sources of neuronal and gial cell production. In this study, the main goal is to investigate the plasticity of these cells in neuronal/astroglial differentiations. To this end, the differentiation of the hipp-NS/PCs isolated from 3-month-old Wistar rats was investigated in response to the embryonic...

Journal: :Bioresource technology 2008
Jong Hyun Yoon Jong-Hwan Shin Tai Hyun Park

The combined effect of superficial gas velocity, pH, initial phosphate concentration, and light intensity on cell growth was investigated for the mass production of cyanobacterial cells. The light intensity was manipulated to maintain a specific irradiation rate (q(i)) at a constant level for high cell density culture. The optimum condition for the batch culture was achieved at a superficial ga...

Journal: :iranian journal of neurology 0
alia saberi poursina hospital, department of neurology, guilan university of medical sciences, rasht, iran. hamid reza hatamian poursina hospital, department of neurology, guilan university of medical sciences, rasht, iran ehsan kazemnejad poursina hospital, department of neurology, guilan university of medical sciences, rasht, iran nasim ghorbannejad poursina hospital, department of neurology, guilan university of medical sciences, rasht, iran

background: some coincidental disorders with migraine have been introduced that may have role in its pathogenesis or aggravation. in this study we determined the relative frequency of hyperlipidemia as a coincidental disorder in patients affected by migraine. methods: a total of 102 migraine-affected patients according to international headache society (his) criteria and 103 control subjects ad...

Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
taravat fakheri homa badri ali mostafaei hamidreza mohammadimotlagh mansour rezaei anisodole nankali

background: uterine leiomyoma is the most common tumor among the female in the reproductive period. the first step to control the tumor is employing medical treatment. currently gnrh agonists are the most common drugs for medical therapy of uterine myoma.  climacteric-like symptoms and osteoporosis and recurrence of the size of tumor after gnrh agonists consumption are among the most common sid...

Journal: :iranian journal of public health 0
ladan delphi houri sepehri elahe motevaseli mohammad reza khorramizadeh

background: collagen-based three-dimensional (3d) in vitro systems have been introduced to study the physiological states of cells. as a biomolecule, collagen is usually extracted from terrestrial animals whilst aquatic animals like squid contain large amounts of collagen. methods: in order to make effective use of marine organisms, we selected persian gulf squid in 2015 to extract the required...

Journal: :acta medica iranica 0
parisa goodarzi clinical grade cell manufacturing facility, brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran. babak arjmand clinical grade cell manufacturing facility, brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran. and endocrinology and metabolism research center, endocrinology and metabolism research institute, tehran university of medical sciences. tehran, iran. seyed hassan emami-razavi clinical grade cell manufacturing facility, brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran. masoud soleimani department of hematology, tarbiat modares university, tehran, iran. abbas khodadadi iranian tissue bank, research and preparation center, tehran university of medical sciences, tehran, iran. fereshteh mohamadi-jahani clinical grade cell manufacturing facility, brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran.

nowadays, cell -based and tissue engineered products have opened new horizons in treatment of incurable nervous system disorders. the number of studies on the role of schwann cells (sc) in treating nervous disorders is higher than other cell types. different protocols have been suggested for isolation and expansion of sc which most of them have used multiple growth factors, mitogens and fetal b...

Journal: :Cancer research 1975
R M Singer L J White J E Perry G J Doellgast

Using exclusion from Sepharose 4B as our criterion, we have found a high-molecular-weight form of alkaline phosphatase and of leucine aminopeptidase which are released into the culture media by the FL amnion cell line. A low-molecular-weight form of leucine aminopeptidase is also found to contribute to the total levels of this enzyme in the media. The levels of these enzymes increased during th...

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