Lymph node enlargement is a common medical problem, and in a large number of patients, the causes of lymphadenopathy remain undiagnosed. We report a thorough microbiological analysis of 1,688 lymph node biopsy specimens collected in our bartonellosis reference center. We studied lymph node biopsy samples from patients with suspected regional infectious lymph node enlargement from January 2008 t...

STUDY DESIGN This case report illustrates a patient presenting with sciatica and diagnosed with epithelioid sarcoma involving the spine. OBJECTIVES The treatment of this patient involved multiple mass resections and decompressions of the spinal canal. Radio- and chemotherapy were applied once a clear diagnosis was obtained. SUMMARY OF BACKGROUND DATA Epithelioid sarcoma is a rare tumor main...

Background: Meningioma is among the most common slow growing central nervous neoplasms, which recurs locally despite the benign histologic features. The aim of this study was to evaluate osteopontin and ki67 expressions in different histologic grades of meningioma in a group of Iranian people. Methods: In this cross-sectional study, first, the paraffin blocks with the definite pathological dia...

Argyrophilic staining of nucleolar organizer regions (AgNOR) has been considered to be useful in the diagnosis and prognostic evaluation of different cutaneous tumors. In order to evaluate the role of the AgNOR technique in discriminating aggressive from non-aggressive basal cell carcinoma (BCC), paraffin-embedded histologic sections from 30 cases of aggressive BCC (BCC2) and 30 cases of n...

BACKGROUND Review of the literature reveals that congenital malignant melanoma is an exceptionally rare occurrence and has a generally poor prognosis when it does occur. However, benign proliferative melanocytic lesions are known to occur within giant congenital nevi (GCN). This entity is not well recognized and can be confused clinically and histologically with malignant change. OBSERVATIONS...

Dermal melanocytic disorders present as bluish pigmentation on the skin. Several entities including Mongolian spot, aberrant nevus of Ota, and Ito have been reported. It is often difficult to distinguish between different from their overlapping features. Although they share similar etiologies histologic findings, co-morbidities prognosis differ. In this paper, we report four cases dermal which ...

Solid variant aneurysmal bone cyst is a rare benign bone lesion, representing a small fraction of all aneurysmal bone cysts. The imaging appearance and histologic features may overlap with other benign and malignant neoplasms, posing a diagnostic dilemma for clinicians, pathologists, and radiologists. We present a case of solid variant aneurysmal bone cyst of the distal fibula and review the ra...

Primordial odontogenic tumor (POT) is a rare characterized by variably cellular loose fibrous tissue with areas similar to the dental papilla and covered cuboidal columnar epithelium. We herein report case of POT in 14-year-old boy. Computed tomography (CT) exhibited round cavity defined cortical border circumscribing tooth second molar. However, gross finding was solid mass, not cyst. Histolog...

PURPOSE To describe the clinical features, histologic findings, flow cytometric immunophenotypes, and molecular profiles of ocular adnexal lymphoid proliferations. STUDY DESIGN Prospective noncomparative case series. PARTICIPANTS Forty-three patients suspected of having ocular adnexal lymphoid proliferations were biopsied and prospectively evaluated. METHODS Provisional diagnoses were mad...

When one reads about the histologic features of celiac disease in a textbook of surgical pathology, it is the absence of normal intestinal villi that generally is stressed as the key diagnostic feature. The features of a “flat mucosa,” in combination with elongation of the intestinal crypts, evidence of epithelial damage, and a variable increase in chronic inflammation of the lamina propria, fo...