Introduction Herein, we developed an engineered extracellular vehicle (EV)-based method for ameliorating inflammatory responses in psoriasis.Methods EVs, derived from annexin A1 (ANXA1) overexpressing T cells, were co-extruded with M2 macrophage membrane to obtain EVs. In vitro, the effect of EVs on polarization was evaluated by real-time PCR. imiquimod (IMQ)-induced psoriasis-like mouse model,...

The present report describes the accidental detection of ectopic intestinal gland like structures with interspersed goblet cells in a mesenteric lymph node from an crossbred adult goat, which was infected with Mycobacterium avium subsp. paratuberculosis. The histomorphological features reminded intestinal epithelium, and glandular choristoma was diagnosed. This report is to our knowledge, the f...