A 63-year-old man presented with dysuria. Ultrasonography revealed a cystic intravesical mass. During needle aspiration we aspirated bloody fluid. The result cytology was class II. We gave medication on an outpatient basis, but symptoms became worse. We performed transurethral resection (TUR) of prostate. Histopathological examination of the TUR specimen revealed a papillary cystadenocarcinoma ...

Mammary Paget’s disease is a rare form of cancer, which involves the nipple-areola complex. In most cases it is associated with an underlying tumor of the breast. Diagnosis is based on clinical appearance and is confirmed by histopathological examination. Imaging tests play an important role in detecting the associated ductal carcinoma. We present the case of a 90-year-old woman, who presented ...

This is a report of a 20-year-old Nigerian man with a 15-year history of exophthalmos and nasal blockage caused by rhinoscleromatous. The diagnosis was made by histopathological examination of a biopsy specimen taken from the nasal passages. Despite protracted antibiotic therapy the patient experienced recurrent exophthalmos. Computerised axial tomography and sinus films showed the lesion to ha...

Histopathological examination of formalin-fixed paraffin-embedded (FFPE) tissues that had been stored for 30 years was conducted, and reconstructivity of the results was verified. These FFPE tissues, which were from all organs of male and female rats, were re-sectioned and histopathologically examined using hematoxylin and eosin (HE) staining. In particular, the stainability and morphology of H...

The National Institute ofHealth Sciences (NIHS) and 18 pharmaceutical companies of the Japan Pharrnaceutical Manufacturers Association (JPMA) have conducted a validation study intended to evaluate whether a 2-week repeated general toxicity period with histopathological examination is suencient to detect ovarian toxicity or not. The current repeated dose general toxicity study is considered to b...

focal epithelial hyperplasia (feh) or heck’s disease is a rare viral infection of the oral mucosa caused by human papilloma virus especially subtypes 13 or 32. the frequency of this disease varies widely from one geographic region and ethnic groups to another. this paper reports an iranian case of extensive focal epithelial hyperplasia. a 35-year-old man with feh is described, in whom the lesio...

This report describes the morphological and immunohistochemical findings of a case of apparent collagenofibrotic glomerulonephropathy in a 7-month-old dog. Clinical examination showed moderate protenuria with elevated blood urea nitrogen and creatinine. Histopathological examination of the glomerular capillary walls and mesangial areas revealed diffuse and global accumulation of eosinophilic ho...

We report a case of Virchow (node) metastasis cervical cancer concurrently with mandibular gingival cancer. A 58-year-old woman was referred to our department complaining inflammation and pain in her right gingiva. histopathological diagnosis squamous cell carcinoma (SCC) obtained by biopsy. FDG-PET/CT showed significant accumulation the cervix left supraclavicular lymph node, suggesting possib...

Sebaceous gland hyperplasia (SGH) is a benign condition that originates in the sebaceous follicles and occurs most commonly on the forehead and cheek. It is very rarely found in the genital region; however, a few case reports have described SGH of the vulva. We recently encountered a case of vulvar SGH in a young woman who presented with an asymmetric labium minus and unilateral vulvar hypertro...

Uveitis is a major cause of vision loss. Methotrexate (MTX) has been widely used in uveitis due to its relatively safe profile. The purpose of this study was to evaluate the effects of two different dosages of MTX via intra-vitreal administration for treatment of endotoxin induced uveitis (EIU) in an experimental model. Thirty-five healthy rabbits were randomly divided into four groups and all ...