Please direct correspondence to Erik Fernandez at [email protected]. Protein unfolding and aggregation can be serious considerations when designing laboratory and preparative chromatographic purification steps. This problem has been studied most thoroughly within the contexts of reversed-phase chromatography and hydrophobic interaction chromatography. However, there are currently no robust meth...

Herein we present a direct label-free ultra-fast method for the identification and classification of the active members of a combinatorial library directly on the solid support used for their synthesis. The method is based on the appropriate functionalization of polyethylene glycol grafted polystyrene (TentaGel®) microbeads with Au@Ag nanoparticles, the use of these materials directly as solid-...

Abstract Fast and accurate screening for mental health problems in early childhood is a prerequisite effective intervention. The Early Childhood Screening Assessment (ECSA) valid standardized tool young children. aims of the current study were to examine psychometric properties, factorial structure, validity evidence test score interpretation German version ECSA. Results confirmatory factor ana...

BACKGROUND Bhutan has been engaged in good-quality cytology-based cervical screening since 2000 and has vaccinated >90% girls against human papillomavirus (HPV) since 2010. We explored the characteristics associated with lack of previous screening and screening coverage in women age ≥25 years. METHODS Women were invited at home or during their attendance at 2 outpatient clinics, in the capita...

The authors examined associations among fast-food consumption, diet, and neighborhood fast-food exposure by using 2000-2002 Multi-Ethnic Study of Atherosclerosis data. US participants (n = 5,633; aged 45-84 years) reported usual fast-food consumption (never, <1 time/week, or > or =1 times/week) and consumption near home (yes/no). Healthy diet was defined as scoring in the top quintile of the Al...

PURPOSE To examine community integration and contributing factors in people with aphasia (PWA) following stroke and to investigate the relationship between community integration and quality of life (QOL). MATERIALS AND METHODS Thirty PWA and 42 age-and education-matched control subjects were involved. Main variables were as follows: socioeconomic status, mobility, and activity of daily living...

OBJECTIVE Inappropriate drug prescription is a common problem in people living in nursing homes and is linked to adverse health outcomes. This study assessed the effect of an educational intervention directed to nursing home physicians in reducing inappropriate prescription and improving health outcomes and resource utilization. DESIGN Prospective, randomized, multicenter study. SETTING A p...

The effect of 2 population-based outreach screening strategies that used in-home sampling was compared with usual care practices for Chlamydia trachomatis infection. All 30,439 persons 21-23 years old in Aarhus County, Denmark, were divided randomly into 3 groups: group 1 (n=4500) had a home sampling kit mailed directly to their centrally registered home address; group 2 (n=4500) had a reply ca...