نتایج جستجو برای: hoxa10
تعداد نتایج: 288 فیلتر نتایج به سال:
Homeotic or homeobox genes represent selector genes involved in the genetic control of development and organization of the body plan. They are characterized by a common highly conserved sequence stretch of approximately 60 amino acids, the homeodomain (McGinnis et al., 1984). In vertebrates, four homeobox gene clusters (HOXA, HOXB, HOXC, and HOXD) have been described (Scott, 1992). In each clus...
Histone methylation is a dynamic and reversible process proposed to directly impact on stem cell fate. The Jumonji (JmjC) domain-containing family of demethylases comprises 27 members that target mono-, di-, and trimethylated lysine residues of histone (or nonhistone) proteins. To evaluate their role in regulation of hematopoietic stem cell (HSC) behavior, we performed an in vivo RNAi-based fun...
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