نتایج جستجو برای: human leukocyte antigen typing
تعداد نتایج: 1819564 فیلتر نتایج به سال:
conclusions our investigation demonstrated that there is a highly significant association between the studied alleles and t1d. it can be construed that haplotype hla-dr3-dq2 has a very modest effect with respect to the risk of t1d. patients and methods this study was a case-control study. the number of samples was determined using the cochran formula. eighty unrelated t1d patients, including 42...
Human leukocyte antigen (HLA) system is the most polymorphic region known in the human genome. In the present study, we analyzed for the first time the HLA-A gene polymorphisms defined by the high-resolution typing methods-sequence-based typing (SBT) in 161 Northern Chinese Han people. A total of 74 different HLA-A gene types and 36 alleles were detected. The most frequent alleles were A*110101...
CONTEXT It is well recognized that celiac disease is an immune-mediated systemic disorder highly prevalent among relatives of celiac patients. OBJECTIVES The aim of this study is to determine the prevalence of celiac disease in a group of first degree relatives of celiac children, and to access the frequency of human leukocyte antigen HLA-DQ2 and DQ8 in celiac disease patients and their affec...
BACKGROUND Successful transfusion of platelet refractory patients is a challenge. Many potential donors are needed to sustain human leukocyte antigen matched-platelet transfusion programs because of the different types of antigens and the constant needs of these patients. For a highly mixed population such as the Brazilian population, the pool size required to provide adequate platelet support ...
Background Patients can form antibodies to foreign human leukocyte antigen (HLA) Class I antigens after exposure allogeneic cells. These anti-HLA class bind transfused platelets (PLTs) and mediate their destruction, thus leading PLT refractoriness. with refractoriness need HLA-matched PLTs, which require expensive HLA typing of donors, antibody analyses patient sera and/or crossmatching. An alt...
Abstract The end result of solid organ transplantation is dictated by selection a well-matched donor, leading to allograft survival. An allogeneic immune response the main immunological barrier for successful transplantation. Donor and recipient human leukocyte antigen (HLA) mismatching results in poor graft acceptance, inflammation rejection. current evaluations donor-recipient HLA incompatibi...
OBJECTIVE To devise a new and simple technique to help select normal embryos that are human leukocyte antigen (HLA) matched to their affected siblings for diseases, such as beta-thalassemia or sickle cell anemia, which are common in this part of the world. METHODS This study was conducted between March 2008 and April 2011 at the preimplantation Genetic Diagnosis Laboratory, Saad Specialist Ho...
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