INTRODUCTION Microarray is a recently developed simultaneous analysis of expression patterns of thousand of genes. The aim of this research was to evaluate the expression profile of human healthy dental pulp in order to find the presence of genes activated and encoding for proteins involved in the physiological process of human dental pulp. We report data obtained by analyzing expression profil...

BACKGROUND Studies examining human and nonhuman primates have supported the hypothesis that the recent increase in the occurrence of misalignment of teeth and/or incorrect relation of dental arches, named dental malocclusion, is mainly attributed to the availability of a more processed diet and the reduced need for powerful masticatory action. For the first time on live human populations, genet...

As right quoted by MT Barrett, “of all the phases of anatomic study in human system, one of the most complex is the pulp cavity morphology.” The external and internal morphology of the tooth varies from person to person. For each tooth in permanent dentition, there is a wide range of variation reported in literature with the respect to frequency of occurrence of the number and shape of the cana...

Dlx (distal-less gene) homeogenes encode transcription factors that are involved in the patterning of orofacial skeleton derived from cephalic neural crest cells. In order to study the role of DLX genes during embryonic development in human, DLX5 expression pattern was investigated in 6- to 11-week-old human embryos. A DLX5 PCR fragment was amplified from a human dental cDNA library subcloned a...

Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines i...

INTRODUCTION Young's modulus (E) and Poisson's ratio (v) of the periodontal ligament are needed in a finite element analysis for investigating the biomechanical behavior of a tooth, periodontal ligament, and bone complex. However, large discrepancies in E (0.01-1,750 MPa) and v (0.28-0.49) were reported previously. The objective of this study was to narrow the ranges and to provide equivalent E...

When a dentist prepares a vital tooth, it is very important to know the distance between the prepared surface and the pulp chamber wall, and now we have developed ultrasonic diagnostic equipment which can indicate the nearness of these two boundaries by measuring the thickness of the remaining dentin. This equipment can be used to measure the thickness of the remaining dentin between the prepar...

introduction: a desirable quality of any endodontic sealer is its ability to be tooth color friendly. therefore the aim of the present study was to evaluate the tooth discoloration potential of a nano zinc oxide-eugenol (nzoe) sealer. methods and materials: in order to evaluate tooth discoloration, the pulp chamber of 60 human maxillary central and lateral incisors were filled with one of the s...

Tooth movement is a biological process of bone remodeling induced by mechanical force. Sclerostin secreted by osteocytes is mechanosensory and important in bone remodeling. However, little is known regarding the role of sclerostin in tooth movement. In this study, models of experimental tooth movement were established in rats and mice. Sclerostin expression was investigated with immunohistochem...

primary tooth impaction is a rare finding during the development of primary dentition. several factors contribute to the impaction of a deciduous tooth. this report describes the diagnosis and treatment of a 10-year-old boy who presented an impacted second primary mandibular molar. this tooth, located inferior to the second premolar together with an odontoma, was positioned superior to the prem...