The majority of hospitals and home respiratory care companies do not use humidification when delivering oxygen at 4 L/ min or 5 L/min via nasal cannula, based on the recommendations of 2 guidelines.1,2 The American Association for Respiratory Care clinical practice guidelines for oxygen therapy1 indicate that oxygen supplied to adults via nasal cannula at flows 4 L/min does not require humidifi...

This study is the first attempt to correlate nivocardial oxygen availability by the polaro-graphic method with direct electrocardiographic leads and cinematographic records of muscle contraction during experimental acute coronary branch occlusion and narrowing. The comparative insensitivity and slowness of the epicardial electrocardiogram as an index of acute regional ischemia is demonstrated. ...

INTRODUCTION Severely burned patients suffering from inhalation injury have a significantly increased risk for mortality compared with burned patients without inhalation injury. Severe burn is associated with a distinct serum cytokine profile and alterations in cytokines that contribute to morbidity and mortality. The aim of the present study was therefore to determine whether severely burned p...

Inhalation of 100% oxygen by nine children with pulmonary vascular disease increased pulmonary blood flow measured at cardiac catheterisation; there was no significant change in pulmonary artery pressure. Fifteen children with pulmonary vascular disease that was severe enough to preclude corrective cardiac operation were studied to determine the effect of long term oxygen treatment on pulmonary...

Values of regional cerebral oxygen extraction ratio and oxygen utilisation obtained with the oxygen-IS steady-state inhalation technique have been found to be overestimated due to the signal from intravascular ox­ ygen-IS. A previously described method to correct for this intravascular component has been applied to a series of studies on normal subjects, and on brain tumour and stroke patients....

Adequate oxygen stress induced by low-dose irradiation activates biodefense system, such as induction of the synthesis of superoxide dismutase (SOD) and glutathione peroxidase. We studied the possibility for alleviation of oxidative damage, such as diabetes and nonalcoholic liver disease. Results show that low-dose γ-irradiation increases SOD activity and protects against alloxan diabetes. Prio...

A patient with migraine who had a permanent visual field defect was studied by angiography and CT scan. He also had a tomographic study of cerebral blood flow (CBF) and oxygen extraction fraction (EO2) using the non-invasive continuous oxygen-15 (15O) inhalation technique. Angiography was normal. CT scan revealed an area of decreased density with contrast enhancement suggestive of a recent infa...

A 69-year-old man with chronic thromboembolic pulmonary hypertension (CTEPH) was on amblatory oxygen inhalation therapy (3 L/min) and scheduled for percutaneous transluminal pulmonary angioplasty (PTPA). The patient's New York Heart Association functional status was class III with recent worsening of dyspnea and apparent leg edema. Transthoracic echocardiography revealed right ventricular enlar...

Prevention and treatment of intraoperative hypoxemia in horses is difficult and both efficacy and safety of therapeutic maneuvers have to be taken into account. Inhaled salbutamol has been suggested as treatment of hypoxia in horses during general anesthesia, due to safety and ease of the technique. The present report describes the occurrence of clinically relevant unwanted cardiovascular effec...

microembolic signals (mes) are frequently observed in transcranial ‎doppler (tcd) recordings of patients with mechanical heart valve (mhv). if gaseous bubbles are the underlying cause, number of mes produced by mhv could be reduced with oxygen ‎inhalation. from september 2003 to september ‎2004, a consecutive series of 14 patients ‎with st jude aortic valve visited in the cardiology clinic were...