Articular cartilage injuries can produce significant musculoskeletal morbidity for both young and active aging patient populations. The complex and highly specialized composition of normal hyaline cartilage makes treatment of focal chondral injuries a formidable challenge for the basic scientist, surgeon, and physical therapist. The current array of surgical treatment options offers palliative,...

We report a case of papillary adenocarcinoma of the sigmoid colon with psammoma bodies and intracytoplasmic hyaline globules. The patient was a 59-year-old woman. The tumor showed central ulceration with smooth elevated ridges. Histologically, the tumor was composed of numerous large irregular tubular structures accompanying infolded papillary growth. The tumor cells showed cytoplasmic basophil...

Right ventricular heart involvement of an otherwise unknown hepatocellular carcinoma is presented and the cytologic differential diagnosis is discussed. This tumor displays classic cytologic features of hepatocellular carcinoma, including trabecular arrangements with prominent endothelial cells and numerous intracytoplasmic hyaline bodies. The background contains many "naked nuclei" and extrace...

Hyaline fibromatosis syndrome (HFS) is rare autosomal recessive disease characterized by the deposition of amorphous hyaline material in skin and visceral organs. It represents a disease spectrum with infantile systemic hyalinosis (ISH) being the severe form and juvenile hyaline fibromatosis (JHF) being the mild form. Dermatologic manifestations include thickened skin, perianal nodules, and fac...

We conducted a prospective, randomized, unblinded, controlled trial of exogenous bovine surfactant (surfactant TA) in premature infants requiring ventilator support for the treatment of severe hyaline membrane disease. Forty-one low birth weight infants with severe hyaline membrane disease were randomly assigned to saline or surfactant therapy and treated within eight hours of birth. Significan...

An increase in the degree of fatty change of the liver was found by Benitez (1952) in babies who had aspirated vernix caseosa or who had pulmonary hyaline membranes, but little else has been recorded about hepatic lesions in such cases. The observation of small thrombi in the sinusoids of the livers of babies with hyaline membranes was thus of interest; the investigation reported in this paper ...