Poly(2-oxazoline)s are regarded as pseudopeptides, thus bioinspired polymers, due to their structural relationship to polypeptides. Materials and solution properties can be tuned by varying the side-chain (hydrophilic-hydrophobic, chiral, bioorganic, etc.), opening the way to advanced stimulus-responsive materials and complex colloidal structures. The bioinspired ―smart‖ solution and aggregatio...

We study experimentally a coiling instability of cylindrical multilamellar stacks of phospholipid membranes, induced by polymers with hydrophobic anchors grafted along their hydrophilic backbone. We interpret our experimental results in terms of a model in which local membrane curvature and polymer concentration are coupled. The model predicts the occurrence of maximally tight coils above a thr...

Hydrogels are hydrophilic, three-dimensional networks able to imprison large amounts of water and largely used in pharmaceutical formulations. frequently obtained from hydrophilic polymers, either natural, biohybrid, or synthetic. Owing their peculiar structure, dendrimers can be considered prospective building blocks for hydrogel networks. This review gathers the use different types amphiphili...

The objective of the present work was to investigate effect various hydrophilic polymers, such as hydroxypropylmethyl cellulose, methyl carboxymethyl cellulose and poly vinyl alcohol, on in vitro dissolution property ibuprofen (IBU) crystallized from aqueous polymeric solutions. By using solvent-change technique, IBU crystal products were produced presence selected polymers. results showed that...

sustained release oral delivery systems are designed to achieve therapeutically effective concentrations of drug in the systemic circulation over an extended period of time. the purpose of the present investigation was to design and evaluate sustained release matrix tablets of nifedipine, a poorly water soluble drug, employing hydroxypropyl methyl cellulose ( hpmc) and ethyl cellulose ( ec) as ...

purpose of this study was to investigate the effect of the presence of the water soluble polymers viz hpmc, pvp and peg 6000 on aqueous solubility and complexation abilities of felodipine with or without presence of β-cyclodextrin (βcd) and hpβcd by phase solubility studies. the data revealed the initial increase in drug solubility followed by plateau in the presence of relatively low polymer c...

The hydrophilic-lipophilic balance (HLB) polymers are able to directly extract polar and non-polar analytes from the aqueous samples, making them very popular for analytical separation SPE applications. However, commonly used suspension polymerization method preparing HLB is only efficiently prepare with low or medium mol percentages of hydrophilic monomer due partitioning into phase at higher ...

cellulose nanofibers (cnf) which isolated from wood and non woody plants have attractive advantages comparing with the synthetic fibers, some of the most relevant being the following: low density, renewable sources, biodegradability, availability, and high specific mechanical properties. recently, the use of cnf in green materials, especially as reinforcement in different polymers has been incr...

This paper reports the fabrication of drug-loaded microspheres by the spray drying method. The microspheres are then compressed by a hydraulic hand press and a die into a disc. The characterization of the microspheres and the effects of different drug loading percentage on the release profile of the drug from the disc are investigated. The effects of different types of polymers used for the fab...

Molecular activity and diffusion coefficients of solvents are important and find wide range of applications to analyze in many problems including polymers, such as polymerization, separation, devolatilization, vacuum/gas stripping and drying. The polyvinyl alcohol (PVA) is a hydrophilic polymer membrane material, which was used extensively in the pervaporation process for dehydration. But due t...