نتایج جستجو برای: hydrophobic modification
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Aalto University, P.O. Box 11000, FI-00076 Aalto www.aalto.fi Author Tiina Nypelö Name of the doctoral dissertation Surface-modified nanoparticles for ultrathin coatings Publisher Aalto University School of Chemical Technology Unit Department of Forest Products Technology Series Aalto University publication series DOCTORAL DISSERTATIONS 12/2012 Field of research Forest Products Chemistry Manusc...
N-terminal acetylation is an abundant modification influencing protein functions. Because ∼80% of mammalian cytosolic proteins are N-terminally acetylated, this modification is potentially an untapped target for chemical control of their functions. Structural studies have revealed that, like lysine acetylation, N-terminal acetylation converts a positively charged amine into a hydrophobic handle...
pluronic/bile salt/phospholipid mixed micelles (pluronic/bs/ps-mm) drug carrier system for solubilization hydrophobic drugs was developed. a typical hydrophobic compound, pyrene, was selected as a representative hydrophobic compound to model the hydrophobic drugs. five pluronics, f68, f88, f98, f108, and f127 with different ppo chain length were studied. cmc data and solubilization capacities w...
Abstract Superhydrophobic surfaces, which have the excellent characteristics of self-cleaning, low-adhesion and non-wetting, been widely used in field biochemical analysis by limiting sample loss. In this paper, a method to generate droplets appropriate volume superhydrophobic holes was proposed. First, super-hydrophobic surface with fabricated laser etching low energy modification. Then, possi...
N(6)A methylation is the most abundant RNA modification occurring within messenger RNA. Impairment of methylase or demethylase functions are associated with severe phenotypes and diseases in several organisms. Beside writer and eraser enzymes of this dynamic RNA epigenetic modification, reader proteins that recognize this modification are involved in numerous cellular processes. Although the pr...
The success of anti-cancer therapies largely depends on the ability of the therapeutics to reach their designated cellular and intracellular target sites, while minimizing accumulation and action at nonspecific sites. Surface modification of nanoparticulate carriers with poly(ethylene glycol) (PEG)/ poly(ethylene oxide) (PEO) has emerged as a strategy to enhance solubility of hydrophobic drugs,...
An organic modification of the surface of titanium dioxide particles precoated with SiO2 and Al2O3 films in a CO2 medium is performed, where CO2 of different phases is used as the solvent and a titanate coupling reagent (CH3)2CHOTi(OP(O)(OH)OP(O)(OC8H17)2)3 is the modification reagent. The results are compared with the modification carried out in a conventional organic solvent. The interaction ...
Polyhydroxyalkanoates (PHA) envisage a potential biomaterial alternative to replacing synthetic polymers for their biodegradability and biocompatibility. Modification approaches exploit the attributes adjust intrinsic hydrophobic properties, such as blending produce new polymer mix with novel properties. Functionalization of PHA, especially chemical grafting, perform introduce additional compou...
The effects of modifying the carbohydrate chain and amino acids on the conformation and activity of Millettia dielsiana Harms. ex Diels. lectin (MDL) were studied by hemagglutination, fluorescence and circular dichroism analysis. The modification of tryptophan residues led to a compete loss of hemagglutinating activity; however, the addition of mannose was able to prevent this loss of activity....
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