We have used the pH-induced self-assembly of a peptide-amphiphile to make a nanostructured fibrous scaffold reminiscent of extracellular matrix. The design of this peptide-amphiphile allows the nanofibers to be reversibly cross-linked to enhance or decrease their structural integrity. After cross-linking, the fibers are able to direct mineralization of hydroxyapatite to form a composite materia...

We presented a case in which massive hydroxyapatite accumulation was observed around the artificial hip joint. A 66-year-old female showed a massive accumulation of fluid in and around the hip joint, and milk-like aspirate was obtained. Her aspirate culture was negative, and sediment analysis by X-ray diffraction showed that its component was hydroxyapatite. Since pain was mild, the patient was...

Hydroxyapatite is the main mineral that makes up bones and teeth so it has a level of similarity with parts can be used as an alternative bone substitute material. As material for substitution, hydroxyapatite fairly high economic value still dominated by imports from foreign countries. In effort to reduce hydroxyapatite, research was carried out on green mussel shells source calcium synthesis h...

Excess urea fertilizer application to the agricultural fields causes severe environmental deterioration. Researchers actively seek safer alternatives, such as nanoparticles with unique properties, reduce chemical inputs without compromising output. In present study, three variants─hydroxyapatite–urea, magnesium-doped hydroxyapatite–urea, and zinc-doped hydroxyapatite–urea nanohybrids─have been ...

An opaque, white chitosan/ Hydroxyapatite nanocomposite was prepared by a simple blend method. Morphology, pore size and dispersion of nano-hydroxyapatite in chitosan matrix were visualized using SEM images. The FTIR with EDX analysis confirmed the bony apatite layer formed on outside composite. Porosity measurements water uptake studies evaluated which revealed maximum porosity 80% to 92% chit...

purpose: to present our experience with cyanoacrylate tissue adhesive in eyes with exposed hydroxyapatite orbital implants. methods: cyanoacrylate tissue adhesive was used in 3 patients with hydroxyapatite orbital implant exposure defects. results: cyanoacrylate glue was applied on the defective area of 3 patients presenting with small exposure (<4mm). the patients were followed for 33 months (...

In 33 dogs we implanted femoral stems made either of carbon composite, some coated with hydroxyapatite, or of titanium alloy with a porous coating. Osseointegration was greater in the hydroxyapatite-coated than in the un-coated stems (p less than 0.001). Push-out tests, at an average of 7.2 months after implantation, showed a six-fold increase in interface shear strength and a twelve-fold incre...

Porous three-dimensional hydroxyapatite scaffolds were synthesised from aragonitic cuttlefish bones via a microwave based technique. Due to its close similarity to the mineral phase found in the natural human bone matrix, synthetically produced hydroxyapatite is considered a viable apatite substitute for natural bone in a number of biomedical applications. The X-ray diffract ion data confirms t...

−− Porous structures were conformed by pressing and heating of hydroxyapatite powders. Samples were obtained in the form of blocks with 47 % porosity. An interval of pore sizes interconnected among 50-120 μm was obtained. The diametrile tensile stress of evaluated samples oscillated between 4 and 21 MPa, according to what has been reported for porous ceramics. The diffraction studies of x-ray o...

background: titanium (ti) implants are commonly coated with hydroxyapatite (ha). however, ha has some disadvantages such as brittleness, low tensile strength and fracture toughness. it is desirable to combine the excellent mechanical properties of zro2 and the chemical inertness of al2o3 with respect to the purpose of this project which was coating ti implants with ha-zro2-al2o3 to modify the s...