Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...

The purpose of this work is to improve the cytocompatibility and corrosion resistance of magnesium alloy in the hope of preparing a biodegradable medical material. The aminated hydroxyethyl cellulose-induced biomimetic hydroxyapatite coating was successfully prepared on AZ31 magnesium alloy surface with a sol-gel spin coating method and biomimetic mineralization. Potentiodynamic polarization te...

OBJECTIVES To compare the effectiveness of bioactive glass (BG), natural hydroxyapatite (HA), and demineralized freeze-dried bone (DFDB) in bone defects. METHODS All animal experiments were conducted in Faculty of Veterinary Medicine, Selcuk University, Konya, Turkey, under the Selcuk University Guidelines for Animal Experimentation, in 2005. Eighteen New Zealand rabbits were used for the exp...

This study proposes boron nitride nanotube (BNNT) reinforced hydroxyapatite (HA) as a novel composite material for orthopedic implant applications. The spark plasma sintered (SPS) composite structure shows higher density compared to HA. Minimal lattice mismatch between HA and BNNT leads to coherent bonding and strong interface. HA-4 wt% BNNT composite offers excellent mechanical properties-120%...

Long-term results are reported in 23 patients and short-term results in 30 patients presenting with bone tumors treated by curettage or resection followed by implantation of hydroxyapatite (HA) or highly purified beta-tricalcium phosphate (beta-TCP), respectively. Mean follow-up was 97 and 26 months in cases involving HA implantation and beta-TCP implantation, respectively. Radiographs revealed...

AIM The aim of the study was to comparatively analyze the in vitro cell adhesion between nano coated titanium dioxide, and calcium hydroxyapatite (HA) coated titanium samples. MATERIALS AND METHODS Nano coated titanium dioxide, and calcium HA were coated onto the titanium samples by drop casting with NAFION membrane and cell culture was done by seeding human osteoblastic sarcoma cells on the ...

This paper reported the uses of ark clam shell calcium precursor in order to form hydroxyapatite (HA) via the wet chemical precipitation method. The main objective of this research is to acquire better understanding regarding the effect of sintering temperature in the fabrication of HA. Throughout experiment, the ratio of Ca:P were constantly controlled, between 1.67 and 2.00. The formation of ...

Hydroxyapatite (HA) is a leading biocompatible material extensively used for bone implants as a porous ceramic graft and as a bioactive coating. Electrical characteristics of HA can be employed in implantable devices for real-time in vivo pressure sensor applications such as in knee or hip prosthesis. In particular, high piezo and pyroelectricity of HA, its polarisation by electron beam and sel...

Abstract Nano-hydroxyapatite (nano-HA) has been widely studied as a promising biomaterial because of its potential mechanical and biological properties. In this article, different synthesis methods for nano-HA were summarized. Key factors the nano-HA, including reactant concentration, effects temperature, PH, additives, aging time, sintering, separately investigated. The performances depend str...

The effects of calcium fluoride (CaF2) additions on the densification and mechanical properties of hydroxyapatite–zirconia composites (HA–ZrO2) were investigated. When small amount of CaF2 was added, the density of the composites was markedly enhanced. The reactions of HA with CaF2, which led to the formation of fluorapatite (FA), were attributed to the observed improvements in densification. W...