OBJECTIVE To study the frequency of retinal toxicity and associated risk factors in a cohort of patients treated with antimalarials and seen at a tertiary level hospital. MATERIAL AND METHODS Retrospective study of 40 patients treated with antimalarials, who were referred to ophthalmology for the study of retinal toxicity during 2011. Data collection included type of antimalarial prescribed, ...

This article aims to understand the pharmacological properties of AZT and analyze possible reasons for its use in treatment COVID-19 alone or associated with chloroquine (CQ) hydroxychloroquine (HCQ). For this, a bibliographical research was carried out following databases: Scientific Electronic Library Online (SciELO), US National Medicine (PUBMED) ScienceDirect. In study, data on pharmacology...

Autoimmune Congenital Heart Block (CHB) is an immune-mediated disease caused by transplacental passage of maternal circulating anti-Ro/SSA and anti-La/SSB antibodies which can bind to fetal cardiac tissue, damaging conduction tissues inflammation fibrosis. Approximately 2% pregnancies with positive anti-Ro will be complicated atrioventricular block the risk recurrence in subsequent 10 times hig...

Background: Hydroxychloroquine (HCQ) has been used against SARS-CoV-2, but large non randomized studies failed to show any clinical benefit. However, in these the drug was started hospital setting, a significant time after onset of symptoms.
 Aim Study: verify if HCQ, given early symptoms and outpatient can reduce admissions improve outcomes COVID-19
 Methods: We performed retrospecti...

Background: Hydroxychloroquine (HCQ) is commonly used for the treatment of various autoimmune diseases. The medication generally well-tolerated. However, long-term use after 5 years may increase risk retinopathy. One study in 2014 has demonstrated can be as high 7.5%. Optical Coherence Tomography (OCT) become a major modality screening Objectives: To evaluate prevalence retinal toxicity among p...

Abstract Background One of the major side effects Hydroxychloroquine (HCQ) is retinopathy. The aim this study was to evaluate Optical coherence tomography angiography (OCTA) parameters in a group patients who have Hydroxychloroquine-induced retinopathy based on Multifocal electroretinography (mfERG) with do not Method This Cross-Sectional Study. In study, Rheumatoid arthritis (RA) or Systemic l...

Objective: In this retrospective observational study, we aimed to investigate the COVID 19 treatment protocols applied in our hospital terms of side effects and 28-day mortality. Methods: All 621 patients diagnosed as COVID-19 treated with any drugs were included study. Inclusion criteria for hospitalization diagnosis being over 18 years old. The divided into 4 groups according treatments again...

Abstract Background and Aim: Natural killer (NK) cells are crucial players of the innate immune system, especially in fight against tumors infections. Besides, NK known to contribute inflammatory processes associated with multiple diseases. The drug hydroxychloroquine (HCQ) has been repurposed be used for treatment malaria, autoimmune diseases, COVID-19 infection. However, its direct mechanism ...

Abstract The concept of moralisation health behaviours was introduced in social psychology to describe the attribution moral properties habits and conditions like smoking or being a vegetarian. Moral are powerful motivators for people institutions, as they may trigger blame, stigma, appraisal, well polarisation interest scientific hype. Here I extend illustrate how medicines treatments can be s...