To the Editor: Martin et al.1 described a meta-analysis of 17 randomized controlled trials evaluating renal function in 1,230 total surgical patients allocated to hydroxyethyl starch (HES) 130/0.4 or control fluid. At baseline, mean serum creatinine (SCr) was lower in HES 130/0.4 recipients than the control group, and after surgery, the most extreme mean SCr values were higher in the patients r...