G.29.505 was used as a single dose induction agent (4 mg/kg) before nitrous oxide and oxygen with halothane or trichloroethylene for the operation of dilatation and curettage. The findings are compared with those of another series in which intermittent injections of G.29.505 supplemented the nitrous oxide. Rapid recovery resulted in a high incidence of coughing and hiccough during the introduct...

17. King JC. Anisotropine methylbromide for relief of gastrointestinal spasm: doubleblind crossover comparison study with belladonna alkaloids and phenobarbital. Curr Ther Res Clin Exp 1966;8(11):535-541. View Abstract 18. Lichstein J, Mayer JD. Drug therapy in the unstable bowel (irritable colon). A 15-month double-blind clinical study in 75 cases of response to a prolonged-acting belladonna a...

years ago. He gave a history of two attacks of what appeared to me to be appendicitis, though the pain was all on the left side. The abdomen appeared rather small, but I thought it would contain the contents of the sac when reduced. I admitted him to my nursing home and gave him careful preparation for three days. On December 15th, I gave him an injection of i gr. morphia and hyoscine gr. ^ + a...

OBJECTIVES The objective of this study was to evaluate the immediate effect of slow pace bhastrika pranayama (respiratory rate 6/min) for 5 minutes on heart rate and blood pressure and the effect of the same breathing exercise for the same duration of time (5 minutes) following oral intake of hyoscine-N-butylbromide (Buscopan), a parasympathetic blocker drug. SUBJECTS AND METHODS Heart rate a...

There are advantages to be gained from using an oral barbiturate as a pre-operative sedative. Heptabarbitone (Medomin) has been given in a dose of 400 mg to fifty healthy patients undergoing minor gynaecological operations. Using a scoring system, the sedative effects of diis drug have been measured and found to be comparable with the sedation produced by papaveretum 20 mg and hyoscine 0.4 mg a...

The objective of this study was to prepare hyoscine butylbromide (a drug with bitter taste) tablets that can rapidly disintegrate in saliva. The granules were prepared by the extrusion method using aminoalkyl methacrylate copolymers (Eudragit E-100). The drugs dissolved rapidly in medium at pH 1.2 in a dissolution test while none of the drugs dissolved from the granules (% of dissolved < 5%) ev...