Physiological dead space (Vds), end-tidal CO(2) (Pet(CO(2))), and arterial CO(2) (Pa(CO(2))) were measured at 1 and 2.8 ATA in a dry hyperbaric chamber in 10 older (58-74 yr) and 10 younger (19-39 yr) air-breathing subjects during rest and two levels of upright exercise on a cycle ergometer. At pressure, Vd (liters btps) increased from 0.34 +/- 0.09 (mean +/- SD of all subjects for normally dis...

Hyperbaric oxygen therapy involves inhaling 100% oxygen at greater than one atmosphere absolute (ATA) in a pressurized chamber. The air we breathe at sea level is defined as 1 ATA. Many of the clinical uses of hyperbaric oxygen therapy (HBOT) have been at pressures above 1.5 ATA. However, recently, some researchers have been using lower pressures of hyperbaric oxygen therapy with good results i...

In order to study the interaction of glutathione, vitamin C and vitamin E under hyperoxia (95 % oxygen) and hyperbaric oxygen (2.5 atmospheric pressure), 20 days old male Guinea pigs were fed with basal vitamin C free diet, while receiving a vitamin C supplement of either high concentration (50 mg/day) or low concentration (1 mg/day) for two weeks. Animals were than exposed to hyperoxia and hyp...

A small body of literature has been published reporting the application of topical oxygen for chronic non-healing wounds . Frequently, and erroneously, this form of oxygen administration has been referred to as "topical hyperbaric oxygen therapy" or even more erroneously "hyperbaric oxygen therapy." The advocates of topical oxygen claim several advantages over systemic hyperbaric oxygen includi...

background : hyperbaric and isobaric bupivacaine has been shown to reduce bispectral index (bis) during spinal anesthesia. the aim of this study was to compare the effect of isobaric bupivacaine and hyperbaric bupivacaine on the bis during cesarean section with spinal anesthesia. methods : in this double-blind randomized controlled clinical trial, 84 pregnant women with asa ( american society o...

Hyperbaric oxygen therapy (HBOT) is the inhalation of 100 percent oxygen inside a hyperbaric chamber that is pressurized to greater than 1 atmosphere (atm). HBOT causes both mechanical and physiologic effects by inducing a state of increased pressure and hyperoxia. HBOT is typically administered at 1 to 3 atm. While the duration of an HBOT session is typically 90 to 120 minutes, the duration, f...

OBJECTIVES We describe the cardiovascular manifestations of carbon monoxide (CO) poisoning. BACKGROUND Carbon monoxide poisoning is a common cause of toxicologic morbidity and mortality. Although the neurologic sequelae of CO poisoning have been well described, the cardiovascular consequences are limited to isolated case reports. METHODS We reviewed the cardiovascular manifestations of 230 ...

Mild-pressure hyperbaric therapy (mHBT) has become increasingly popular among elite athletes and most recently among the general public yet there is very little scientific underpinnings on its therapeutic use. In this study, fifteen healthy volunteers (8 men, 7 women, mean age 29.7 ± 8.1 years) were exposed to 1.3 atmospheres absolute (ATA) for 40 minutes in a mild hyperbaric chamber called “Oa...

The subjects in the study were 111 patients with open angle glaucoma who were submitted to treatment by hyperbaric oxygenation. Two groups were formed at random, an experimental one of 91 patients and a control group of 20 patients. The experimental group consisted of four subgroups classified according to the course of treatment they received: 30 sessions (31 patients), 20 sessions (20 patient...