نتایج جستجو برای: hyperlipidaemia

تعداد نتایج: 1227  

Journal: :Archives of disease in childhood 1977
M El-Bishti R Counahan R J Jarrett L Stimmler V Wass C Chantler

Fasting plasma concentrations of triglycerides (TG), cholesterol, immunoreactive insulin (IRI), and blood glucose were raised in 16 children with chronic renal failure on regular haemodialysis compared with 18 healthy children. In the patients plasma IRI correlated positively with plasma TG, while blood glucose did not correlate with IRI or lipid concentrations. Dietary intake, expressed as per...

Journal: :Biochemical Society transactions 2003
M Castro Cabezas

FCHL (familial combined hyperlipidaemia) is the most frequent inherited disorder of lipid metabolism leading to premature atherosclerosis. The usual phenotype in FCHL is elevated fasting plasma triacylglycerols, low HDL (high-density lipoprotein)-cholesterol concentrations and elevated plasma apolipoprotein B concentrations. The metabolic basis for this phenotype is hepatic overproduction of VL...

Journal: :Journal of medical genetics 2008
M Abifadel L Bernier G Dubuc G Nuel J-P Rabès J Bonneau A Marques M Marduel M Devillers A Munnich D Erlich M Varret M Roy J Davignon C Boileau

BACKGROUND Our discovery in 2003 of the first mutations of PCSK9 gene causing autosomal dominant hypercholesterolaemia (ADH) shed light on an unknown factor that strongly influences the level of circulating low density lipoprotein cholesterol (LDL-C). PCSK9 gain of function mutations cause hypercholesterolaemia by a reduction of LDL receptor levels, while PCSK9 loss of function variants are ass...

Journal: :Expert Opinion on Investigational Drugs 2017

2005
R. J. A.

The rising incidence of coronary heart disease (CHD) in affluent populations has focused attention onto predisposing risk factors, among them high blood levels of cholesterol and triglyceride. In some inherited disorders characterized by hyperlipidaemia the risk of developing CHD is extremely high, and attempts at preventing CHD should in the main concentrate on these individuals in view of the...

2014
Syed Neyaz Hasan Deepankar Singh Salman Shafi Siddiqui Megha Kulshreshtha Tanu Aggarwal

Introduction: Hyperlipidaemia is a major risk factor for cardiovascular diseases and may be associated with metabolic syndrome. Olive oil contains monounsaturated fatty acids (MUFA) and various phytochemicals which have beneficial role in hyperlipidaemia. Objective The present study was conducted to explore the antihyperlipidaemic effect of olive oil. Methods -We studied 60 hyperlipidaemic male...

Journal: :The journal of family planning and reproductive health care 2010
Rudiger Pittrof Punam Rubenstein Ulrike Sauer

for obesity could possibly have reduced confounding, but it would not have eliminated it, especially since its effect in combination with other risk factors is multiplicative. With regard to possible confounding from other sources, VTE was more frequently diagnosed in women who only completed primary school. Socioeconomic status was thus a determinant of VTE risk, and the possibility that this ...

Journal: :Postgraduate medical journal 1993
D J Fernando S Siribaddana N Perera S Perera D de Silva

The prevalence of macrovascular disease and hyperlipidaemia was examined in 500 patients with non-insulin-dependent diabetes mellitus attending a diabetic clinic in a Sri Lankan teaching hospital and 250 controls matched for age and gender. Macrovascular disease was assessed using a modified World Health Organisation questionnaire and modified Minnesota coding of electrocardiogram recordings. T...

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