BACKGROUND AND AIMS Retrospective, observational study to compare clinical symptoms and TSH-receptor antibodies (TRAb) in Graves ophthalmopathy (GO) in euthyroid and primarily hypothyroid patients to those in hyperthyroid patients. METHODS Clinical symptoms (NOSPECS (severity) and CAS (activity) score), prevalence and levels of thyroid specific antibodies and the course of the disease were ev...

Hyperthyroidism induces marked changes in hemodynamics. Although considerable research has been done to study the effect of hyperthyroidism on the cardiovascular system, few studies have isolated the short-term, nongenomic effects of thyroid hormone on cardiovascular responses to exercise. We used near-infrared spectroscopy to measure muscle oxygenation, Doppler ultrasound to measure skeletal m...

Development of mammary tumors in primiparous C3H/HeN mice (mouse mammary tumor virus positive) in various thyroid states was followed for one year after removal of pups. Animals were either euthyroid or made hyperthyroid (by ingestion of thyroxine) or hypothyroid (by ingestion of 2-thiouracil) during involution. These manipulations resulted in significant changes in serum 3,5,3'-triiodo-L-thyro...

1. The metabolism of glucose, glutamine and ketone-bodies was studied in the small intestine of rats after 5 days of hyperthyroidism. 2. Portal-drained visceral bloodflow increased by 20.1% (P < 0.05) in hyperthyroid rats and was accompanied by a decrease in the arteriovenous concentration difference of glutamine (25.7%, P < 0.05), glutamate (22.0%, P < 0.05), alanine (20.9%, P < 0.05) and ammo...

Objective: To see the impact of abnormal secretion thyroid hormones on red cell indices in patients disorders. Study Design: Descriptive Cross Sectional study. Setting: Department Pathology, Sahiwal Teaching Hospital, Sahiwal. Period: September 2020 to March 2021. Material &amp; Methods: Two hundred and thirty four (234) disorders were enrolled total, out which 44 hyperthyroid, 102 euthyroid 88...

(Na+ + K+)-dependent ATPase activity, heat production and oxygen consumption were increased by 59%, 62% and 75% respectively in hepatocytes from tri-iodothyronine-treated rats. Ouabain at concentrations of 1 and 10 mM decreased oxygen uptake by 2--8% in hepatocytes from euthyroid rats and by 5--15% in hepatocytes from hyperthyroid animals. Heat output was decreased by 4--9% with the glycoside i...

thyroid gland dysfunction is associated with disorders of female reproductive functions. the aim of this study was to examine the effects of hyperthyroidism on ovulation rate and peripheral sex steroid levels in prepubertal and adult rats. two groups of female rats aging 30 days (prepubertal rats) and 60 days (adult rats) were made hyperthyroid by oral administration of levothyroxine daily. in ...