INTRODUCTION AND OBJECTIVES To compare two equations for evaluating coronary risk, the Framingham-Wilson equation and the Framingham equation adjusted for the Spanish population (REGICOR), in a group of dyslipidemic patients in our healthcare area. In addition, the therapeutic implications of using the 2 methods were also evaluated. PATIENTS AND METHOD The study included 815 dyslipidemic pati...

Anti-diabetic effects on the metabolomic differences between green tea (GT) and Aquilariae lignum-fermented green tea (fGT) were investigated in the high fat-fed mouse. To prove the differences, hypoglycemic (blood glucose, insulin and glycated hemoglobin levels, pancreas weights and histopathological-immunohistochemistrical analysis of pancreas-insulin/glucagon cells), hepato- and nephron-prot...

Ethanolic extracts of Canarium schweinfurthii stem bark and Senna alata leaf, and aqueous extract of unripe Carica papaya fruit, at two different doses (150, 400 mg/kg), were evaluated for antihyperglycaemic and hypolipidemic effects on alloxan-induced diabetic rats following daily oral administration for 28 days. While antihyperglycaemic effect was lacking in Senna alata, it was persistent (P<...

In this study, the hypolipidemic effect of exopolysaccharides (EPS) from Pleurotus geesteranus 5# fermenting liquor by the optimal culture conditions in a 5-L stirred-tank reactor was investigated. The hypolipidemic effect of the polysaccharide, investigated in streptozotocin induced diabetic mice, decreased plasma glucose, total cholesterol and triacylglycerol concentrations by 17.1 %, 18.8 % ...

Resveratrol is a nonflavonoid polyphenolic compound which has a broad range of desirable biological actions which include antioxidant, anti-inflammatory, antidiabetic, cardioprotective, and antitumor activities. However, there is concern that the bioavailability of resveratrol may limit some of its clinical utility. So, the aim of this study was to enhance the dissolution rate and oral hypoglyc...

objectives: diabetes mellitusmanifests itself in a wide variety of complications and the symptoms of this disease are multifactorial. previousstudies proved that this disease is directly related to hyperglycemia and hyperlipidemia. the aim of this study was to investigate the hypoglycemic and hypolipidemic effects of hydroalcoholic extract of prangos frulacea (l.)lindlin alloxan-induced diabeti...