Tumor suppressor p53 is involved in regulating immune responses, which contribute to antitumor and antiviral activity. However, whether p53 has anti-bacterial functions remains unclear. Listeria monocytogenes (LM) causes listeriosis in humans and animals, and it is a powerful model for studying innate and adaptive immunity. In the present study, we illustrate an important regulatory role of p53...

Given an instance of TSP together with an optimal solution, we consider the scenario in which this instance is modified locally, where a local modification consists in the alteration of the weight of a single edge. More generally, for a problem U , let LM-U (local-modification-U ) denote the same problem as U , but in LM-U , we are also given an optimal solution to an instance from which the in...

Bir bireyin içine do?du?u grubun veya toplumun bir parças? olma süreci sosyalle?me olarak adland?r?l?r ve bu süreçte e?itimin önemli yeri vard?r. Büyük ya da küçük, geleneksel modern her toplum üyelerinden mümkün oldu?u kadar çok katk? sa?lamas?n? bekler. Ancak tek yönlü süreç beklenti de?ildir. Özellikle dünyada kurumsalla?an örgütlü yap? içerisinde gerçekle?en örgün e?itim öncelikli ihtiyaçla...

We have obtained 3.3–3.4-lm spectro-images of Jupiter including CH4 and H3 emission lines from both polar regions at the Gemini North telescope. We find that the peak of the 3-lm CH4 northern bright spot is located at 200 (SysIII) longitude, 20 west of the center of the 8-lm north-polar bright spot, and does not coincide with the 3-lm H3 bright spot. We derive high temperatures (500–850 K) from...

BACKGROUND & AIMS Lean mass (LM) is an important parameter in clinical outcomes, which highlights the necessity of reliable tools for its estimation. The adductor pollicis muscle thickness (APMT) is easily accessible and suffers minimal interference from the adjacent subcutaneous fat tissue. OBJECTIVE To assess the relationship between the APMT and LM in a sample of Southern Brazilian adults....

Concurrent meniscal repair with anterior cruciate ligament (ACL) reconstruction has shown good clinical outcomes, but it has a considerable risk of progressing to post-traumatic osteoarthritis of the knee. Here we investigated postoperative changes in the position of the lateral meniscus (LM) and assessed the short-term clinical results after concurrent LM repair with ACL reconstruction. Twenty...

The Oriens-lacunosum moleculare (O-LM) subtype of interneuron is a key component in the formation of the theta rhythm (8 12 Hz) in the hippocampus. It is known that the CA1 region of the hippocampus can produce theta rhythms in vitro with all ionotropic excitation blocked, but the mechanisms by which this rhythmicity happens were previously unknown. Here we present a model suggesting that indiv...