background & objectives:  methicillin resistance staphylococcus aureus (mrsa) is one of the most important pathogens that causes several nosocomial and community infections. adhesion to surfaces and biofilm formation is considered main step in staphylococcal infection. the aims of this study were to determine presence oficaabcd genes and relation to the biofilm formation in of mrsa isolates...

Staphylococcus epidermidis is a commensal skin bacterium that forms host- and antibiotic-resistant biofilms are major cause of implant-associated infections. Most research has focused on studying the responses to host-imposed stresses planktonic bacteria. In this work, we addressed open question how S. thrives toxic concentrations nitric oxide (NO) produced by host innate immune cells during bi...

Staphylococcus aureus is an important pathogen involved in subclinical bovine mastitis, causing high economic losses for the dairy industry. The successful persistence of this host occurs due to a series factors associated with colonization ability and acquisition virulence factors. This bacterial species carries genetic heterogeneity, genetically diverse strains characterize population. Analys...

PNAG is a major component of Staphylococcus epidermidis biofilms involved in intercellular adhesion as well as in the interaction of the biofilm with components of the host immune response. Synthesis of PNAG has been found to be regulated by several environmental factors. In the present study, the effect of glucose metabolism-dependent culture medium acidification in PNAG accumulation was evalu...

The atlC gene (1,485 bp), encoding an autolysin which binds fibronectin, and the ica operon, involved in biofilm formation, were isolated from the chromosome of an infectious isolate of Staphylococcus caprae and sequenced. AtlC (155 kDa) is similar to the staphylococcal autolysins Atl, AtlE, Aas (48 to 72% amino acid identity) and contains a putative signal peptide of 29 amino acids and two enz...

Staphylococcus epidermidis, especially methicillin-resistant strains, may be the source of surgical site infections and may be a reservoir of staphylococcal cassette chromosome mec (SCCmec) for S. aureus. The aim of this study was to investigate the prevalence of methicillin-resistant S. epidermidis (MRSE) on the abdominal skin of females before laparotomy and determine the molecular characteri...

INTRODUCTION Burns are the most serious forms of trauma and a major cause of mortality worldwide. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common pathogens of burn wound infections; treatment has faced serious problems due to antibiotic resistance in these strains. Biofilm formation, which increases antibiotic resistance capabilities and is considered to be a virule...

Biofilm formation in Staphylococcus aureus under in vitro growth conditions is generally promoted by high concentrations of sugar and/or salts. The addition of glucose to routinely used complex growth media triggered biofilm formation in S. aureus strain SA113. Deletion of ccpA, coding for the catabolite control protein A (CcpA), which regulates gene expression in response to the carbon source,...