نتایج جستجو برای: idiopathic parkinson disease
تعداد نتایج: 1538852 فیلتر نتایج به سال:
background: free radical formation and oxidative stress might play an important role in the pathogenesis of parkinson's disease (pd). in vitro data indicate that neuromelanin (nm) pigment is formed the excess cytosolic catecholamine that is not accumulated into synaptic vesicles via the vesicular monoamine transporter 2 (vmat2). we designed this study to investigate the neuroprotective eff...
antioxidants have protective effects against free radicals-induced neural damage in parkinson's disease (pd). we examined the effects of ellagic acid (ea) on locomotion, pallidal local eeg, and its frequency bands' power and also cerebral antioxidant contents in a rat model of pd induced by 6-hydroxidopamine (6-ohda). 6-ohda (16 µg/2µ l) was injected into the right medial forebrain bundle (mfb)...
the aim of this work is to use self organizing map (som) for clustering of locomotion kinetic characteristics in normal and parkinson’s disease. the classification and analysis of the kinematic characteristics of human locomotion has been greatly increased by the use of artificial neural networks in recent years. the proposed methodology aims at overcoming the constraints of traditional analysi...
The effects of the inflammatory mediators involved in systemic lupus erythematous (SLE) on subsequent Parkinson disease have been reported, but no relevant studies have focused on the association between the 2 diseases. This nationwide population-based study evaluated the risk of Parkinson disease in patients with SLE.We identified 12,817 patients in the Taiwan National Health Insurance databas...
A case of idiopathic hypertrophic subaortic stenosis (IHSS) associated with Wolff-Parkinson-White (WPW) syndrome is studied. On three occasions preexcitation was suppressed with an intravenous injection of ajmaline. The left ventricular outflow tract obstruction (LVOTO) was analyzed; when WPW syndrome activation disappeared, the obstruction decreased. The ventricular depolarization pathway is n...
Genome-wide analysis of a multi-incident family with autosomal-dominant parkinsonism has implicated a locus on chromosomal region 3q26-q28. Linkage and disease segregation is explained by a missense mutation c.3614G>A (p.Arg1205His) in eukaryotic translation initiation factor 4-gamma (EIF4G1). Subsequent sequence and genotype analysis identified EIF4G1 c.1505C>T (p.Ala502Val), c.2056G>T (p.Gly6...
INTRODUCTION This epidemiological survey estimates the hospitalization burden related to Parkinson´s Disease in Spain. METHODS This observational retrospective survey was performed by reviewing data from the National Surveillance System for Hospital Data, which includes more than 98% of Spanish hospitals. All hospitalizations of patients with Parkinson´s disease that were reported from 1997-2...
Objective. To determine and describe the pathophysiological aspects of oropharyngeal swallowing in patients with Parkinson's disease more accurately, a pilot study of qualitative as well as quantitative parameters of swallowing was performed using videofluoroscopy (VFS). Methods. Ten patients with a diagnosis of idiopathic Parkinson's disease having dysphagic complaints and ten healthy age- and...
Certain dopaminergic anti-Parkinson drugs (ergolines) have repeatedly been identified as a cause of pleuropulmonary disease with a focus on serosal cell damage. Recently, a pathogenetic link between ergolines and prior asbestos exposure was suggested, as regards the development of pleural pathology. This report describes a patient with idiopathic Parkinson's disease, who was on a multiple drug ...
Dopamine receptors are abundant along the central nigrostriatal tract and expressed as 5 subtypes in two receptor families. In PD, compensatory changes dopamine emerge a consequence of loss nerve terminals or dopaminergic pharmacotherapy. We performed systematic review meta-analysis available PET single-photon emission computed tomography studies that have investigated PSP MSA. The inclusion cr...
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