background: interleukin (il)-23 and il-27 are two il-12-related cytokines which their function may dramatically influence the inflammatory response to tumor development. il-12 and il-27 seem to have antagonistic roles with il-23 in tumor site. in this study, il-23 and il-27 mrna expressions were analyzed in peripheral blood of patients with breast cancer and healthy volunteers using quantitativ...

BACKGROUND Interleukin (IL)-10, IL-6 and their ratio (IL-6/IL-10) play an important role in the risk of developing coronary artery disease, and may correlate with its outcomes. Few clinical trials have investigated the prognostic impact of these factors on long-term cardiovascular events in patients presented with chest pain. METHODS A prospective study was performed on 566 patients admitted ...

One of the typical and mandatory reactions body to trauma or infectious agents for damage any tissues organs is acute phase reaction, which an induced increase in synthesis followed by blood a number proteins with immunological, bactericidal, antioxidant inhibitory functions. The purpose study determine levels cytokines clinically healthy cows, pigs dogs, as well cows purulent-necrotic processe...

Cytokines produced in the tumour microenvironment have an important role in cancer pathogenesis. Altered cytokine expression may result in increased susceptibility to and/or poor prognosis in certain cancers. Therefore, the aim of this study was to investigate the influence of interleukin (IL)-8 and IL-10 on sporadic colon cancer development and progression. In our study, a statistically signif...

Background: Multiple Sclerosis is the most prevalent disease of the central nerve system. This disease affects different aspects of patient’s life. Multiple Sclerosis has negative effects on physical and mental health. Cytokines play an important role in the pathogenesis of Multiple Sclerosis and are major targets of therapeutic interventions. Aim: To investigate the effects of aquatic aerobic ...

CONTEXT Chronic systemic inflammation in obesity originates from local immune responses in visceral adipose tissue. However, assessment of a broad range of inflammation-mediating cytokines and their relationship to physical activity and adipometrics has scarcely been reported to date. OBJECTIVE To characterize the profile of a broad range of pro- and anti-inflammatory cytokines and the impact...

Ischemia induces both hypoxia and inflammation that trigger angiogenesis. The inflammatory reaction is modulated by production of anti-inflammatory cytokines. This study examined the potential role of a major anti-inflammatory cytokine, interleukin (IL)–10, on angiogenesis in a model of surgically induced hindlimb ischemia. Ischemia was produced by artery femoral occlusion in both C57BL/6J IL-1...