نتایج جستجو برای: immune modulation

تعداد نتایج: 407631  

Journal: :Frontiers in Cell and Developmental Biology 2016

Journal: :International Journal of Molecular Medicine 2014

Journal: :Expert reviews in molecular medicine 2008
Meera Ramanujam Anne Davidson

Systemic lupus erythematosus (SLE) is a complex immune disorder in which loss of tolerance to nucleic acid antigens and other crossreactive antigens is associated with the development of pathogenic autoantibodies that damage target organs, including the skin, joints, brain and kidney. New drugs based on modulation of the immune system are currently being developed for the treatment of SLE. Many...

Christian Thomas, Ole Simon, Oliver Grauer, Petra Hundehege, Sven Meuth, Thomas Müntefering, Tobias Ruck,

TASK-3, a two-pore-domain (K2P) potassium channel, has been implicated as important regulator for the effector function and proliferation of T-cells. Interestingly, TASK-3 has also a functional impact on tumor cells. Therefore, we sought to investigate whether TASK3 modulation might have a therapeutic potential for malignant gliomas by a variety of phenotypical and functional in vitro assays mi...

Rahees T, Sibi Perumbamkudiyil Ittiyavirah,

Immunomodulation is a procedure, which can alter the immune system of an organism by interfering its function. Modulation of immune system may result in suppression or stimulation of immunological reactivity. Recently the effect of immunomodulators in the treatment of various diseases is significant. Tinosporacordifolia is a widely used shrub in ayurvedic system of medicine. It is reported ...

2017
Jiuwei Cui Guozi Yang Zhenyu Pan Yuguang Zhao Xinyue Liang Wei Li Lu Cai

The interrelationship between ionizing radiation and the immune system is complex, multifactorial, and dependent on radiation dose/quality and immune cell type. High-dose radiation usually results in immune suppression. On the contrary, low-dose radiation (LDR) modulates a variety of immune responses that have exhibited the properties of immune hormesis. Although the underlying molecular mechan...

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