background: beta-thalassemia major is one of the major health problems in our country. many studies have confirmed the fact that, these patients have an increased susceptibility to bacterial infections. objective: in this study, we have assessed the humoral immune system in 68 thalassemic patients by measuring their serum concentration of immunoglobulin g (igg), igm, iga, c3 and c4 in order to ...

Objective: To determine the risk factors of infection in patients with nephrotic syndrome. Methods: A retrospective study was conducted on 155 syndrome under our department from January 2019 to December 2019. Among them, 43 cases had infection, and rate 27.74%. The were analyzed. Results: syndrome, developed including 3 upper respiratory tract (6.98%), 33 lower (76.74%), skin (6.97%), urinary 1...

Myotonic dystrophy is a hereditary progressive muscular abnormality with dominant transmittance that was first proposed as a separate entity by Batten and Gibb (1) and by Steinert (2) in 1909. The muscular abnormality that is the dominant feature of the disease is characterized by weakness, wasting, and myotonia, especially of the facial, neck, and distal musculature. Other abnormalities freque...

Summary Neonates are born with an immature immune system and rely on the transfer of immunity from their mothers. Maternal antibodies transferred via placenta breast milk. Although role placentally immunoglobulin G (IgG) is established, less known about selection milk mechanisms by which they provide protection against neonatal disease. Evidence suggests that play multifaceted roles, p...

Aims Postural tachycardia syndrome (POTS), a common and debilitating cardiovascular disorder, is characterized by an exaggerated heart rate increase during orthostasis and a wide spectrum of adrenergic-related symptoms. To determine the aetiology of POTS, we examined a possible pathophysiological role for autoantibodies against α1-adrenergic (α1AR) and β1/2-adrenergic receptors (β1/2AR). Meth...

Secretory immunoglobulin A (SIgA) and immunoglobulin G (IgG) antibody-secreting cells (ASCs) are two important cell types in the mucosal immune system. This study aimed to explore the distribution of these ASC populations in the small intestine of Bactrian camels of different ages. Twenty-four Alashan Bactrian camels were divided into the following four age groups: young (1-2 years), pubertal (...

The abilities of deglycosylated or pH-denatured and renatured rabbit immunoglobulin G (IgG) antibodies to interact with antigen and the first component of complement, Clq, were studied to begin probing the environmental features of immunoglobulin domains required for the first step in activating the classical complement pathway. Both immune complex formation and the binding of haptens, natural ...

objectives: ctxb (cholera toxin b subunit) contributes to a vaccine's efficacy by stimulating production of the anti-ctxb antibody. various attempts have been made to increase production of this antibody. chitosan is a mucoadhesive polysaccharide that has tremendous potential for oral vaccine delivery in terms of its exclusive features that include biocompatibility, biodegradability, high charg...

background and purpose: although molds are regarded as the main fungal allergen sources, evidence indicates that spores of basidiomycota including agaricus bisporus (a. bisporus) can be also found at high concentrations in the environment and may cause as many respiratory allergies as molds. the aim of the present study was to evaluate specific immunoglobulin e (ige) and immunoglobulin g (igg) ...