BACKGROUND This study investigated postpartum metabolic abnormality in women with previous gestational diabetes mellitus (GDM) and predictive factors for postpartum glucose intolerance. METHODS From March 2001 to February 2003, 127 prior-GDM women underwent a 75g oral glucose tolerance test (OGTT) and metabolic assessment at least six weeks after delivery. To identify the predictors, clinical...

BACKGROUND The aim of this study is to investigate the need for diabetes primary prevention program in isolated impaired fasting glucose (i-IFG) of the first degree relatives of type 2 diabetics. METHODS In a cross sectional study, 793 individuals with prediabetes [543 with i-IFG and 250 with isolated impaired glucose tolerance (i-IGT)] who were the first degree relatives of type 2 diabetic p...

See online version for legend and references. systemic IR Apparently normal intrauterine growth and development, severe hyperglycemia and hyperke-tonemia, perinatal death as the result of diabetic ketoacidosis within 48–72 hours IRS-1 Retarded embryonal and postnatal growth, insulin resistance, normal fasting glycemia and normal or mild glucose intolerance, hyperinsulinemia IRS-2 Insulin resist...

Background: Prediabetes is a metabolic condition which is characterized by the presence of higher levels of blood glucose. It can be treated by lowering high blood glucose level and maintaining the healthy lifestyle habits, healthy meal plan and regular exercise. The aim of this study was to evaluate the prevalence of prediabetes and to identify the risk factors involved in its progression. Ma...

UNLABELLED Insulin binding, glucose transport, and glucose oxidation were studied in isolated adipocytes obtained from fasting rats. Fasting led to an increase in the overall binding affinity for insulin, while the number of receptor sites per cell remained constant. Glucose oxidation was markedly attenuated during fasting. Basal rates of oxidation decreased by about 50%, while insulin-stimulat...