نتایج جستجو برای: indoxyl sulfate

تعداد نتایج: 58952  

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2012
Hiroshi Watanabe Tsuyoshi Noguchi Yohei Miyamoto Daisuke Kadowaki Shunsuke Kotani Makoto Nakajima Shigeyuki Miyamura Yu Ishima Masaki Otagiri Toru Maruyama

Recently, p-cresyl sulfate (PCS) has been identified as a protein-bound uremic toxin. Moreover, the serum-free concentration of PCS, which is associated with its efficacy of hemodialysis, appears to be a good predictor of survival in chronic kidney disease (CKD). We previously found that PCS interacts with indoxyl sulfate (IS), another sulfate-conjugated uremic toxin, during renal excretion via...

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