BACKGROUND Metastasis to multiple stations of mediastinal nodes is associated with a poor prognosis. OBJECTIVE : We prospectively examined the efficacy of induction therapy plus surgery in patients with non-small cell lung cancer and metastases at multiple stations of mediastinal (N2) lymph nodes. METHODS Among the 1,085 patients who underwent surgery for primary non-small cell lung carcino...

ABSTRACTOvulation induction with clomiphene citrate is a hormonal therapy for infertile women impaired ovarian function caused by dysregulation of the hypothalamus and pituitary, affecting egg development ovulation. Several factors, such as obesity, influence success rate treatment citrate. According to Asia-Pacific classification, obesity was classified into two categories, type I (25-29,9 kg/...

A consistently increased mRNA expression of the adhesion receptor CD11b is a hallmark of the reported genomewide gene expression changes in precursor B-cell acute lymphoblastic leukemia (PBC-ALL) after 1 week of induction therapy. To investigate its clinical relevance, CD11b protein expression in leukemic blasts has been prospectively measured at diagnosis (159 patients) and during therapy (53 ...

INTRODUCTION The treatment of acute myeloid leukemia (AML) consists of induction therapy with anthracyclines and cytarabine followed by two to four cycles of consolidation therapy with high-dose cytarabine after achieving remission. There have been very few studies comparing infections during induction and consolidation. We have analyzed blood cultures of patients with AML during episodes of fe...

Cure rates for adult acute lymphoblastic leukaemia (ALL) in developing countries are significantly lower because of problems unique to these countries. Recent studies have reported complete response rates for any induction regimen of more than 90% in adult ALL patients. This study was conducted to evaluate the response rate of induction chemotherapy in adult ALL patients in the Department of Ha...

We investigated the changes in energy expenditure during induction therapy in patients with severe or moderate ulcerative colitis. Thirteen patients (10 men, 3 women; mean age, 36.5 years) with ulcerative colitis admitted to the Shiga University Hospital were enrolled in this study. We measured the resting energy expenditure and respiratory quotients of these patients before and after induction...

BACKGROUND The existence of circulating tumor cells (CTCs) in patients with lung cancer has been reported. The purpose of this study was to assess whether CTCs are predictive of the pathological effects of induction chemoradiotherapy for patients with non-small cell lung cancer. METHODS Patients who underwent induction chemoradiotherapy followed by surgery were compared with those who underwe...

OBJECTIVE To determine the prevalence of hyperglycemia during induction therapy in adult patients with acute leukemia and its effect on complicated infections and mortality during the first 30 days of treatment. METHODS An analysis was performed in a retrospective cohort of 280 adult patients aged 18 to 60 years with previously untreated acute leukemia who received induction chemotherapy from...

Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiological syndrome, characterized by acute onset of headache, altered mental status, visual impairment, nausea, vomiting, seizure, hypertension. PRES condition if it recognized early, but neurological damage or even death may occur. Herein, we present two cases ALL who developed during their induction therapy literature re...

Introduction: Periorbital wrinkles are very common and permanent cutaneous folds that develop on the periocular area. The treatment for wrinkles varies with the degree of severity. A relatively new treatment, called collagen induction therapy (CIT), seems to be appropriate for the treatment of periorbital wrinkles. Objective: To confi rm the usefulness of CIT in periorbital wrinkles treatment. ...