The efficient separation of exfoliated malignant tumor cells (MTCs) from pleural and peritoneal effusions is critical for improving the detection sensitivity reducing time-consuming cytological assessment. Herein, an...

Rapidly increasing fields, such as systems biology, require the development and implementation of new technologies, enabling high-throughput and high-fidelity measurements of large systems. Microfluidics promises to fulfill many of these requirements, such as performing high-throughput screening experiments on-chip, encompassing biochemical, biophysical, and cell-based assays. Since the early d...

BACKGROUND The precise measurement of cell-free fetal DNA in maternal plasma facilitates noninvasive prenatal diagnosis of fetal chromosomal aneuploidies and other applications. We tested the hypothesis that microfluidics digital PCR, in which individual fetal-DNA molecules are counted, could enhance the precision of measuring circulating fetal DNA. METHODS We first determined whether microfl...

Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, microfluidics has not yet been adopted widely. It is increasingly realized that an effective system i...

We introduce a droplet-jumping phenomenon on a superhydrophobic surface driven by the resonant AC electrowetting. The resonant electrical actuation enables a droplet to accumulate sufficient surface energy for jumping, and superhydrophobic surface minimizes adhesion and hysteresis effects. They provide the effective energy conversion from the surface energy to the kinetic energy and improve the...

A specific form of the inertial law is presented by which we can gain a deeper insight into the essence of mass and inertia. In this modified theory, there is no need to keep the concept of absolute space and Newton's third law as principles, By introducing a convenient form for gravitational law the coupling constant G becomes a function of inertial parameters of the universe