With advancements in the care of preterm infants, the goals in nutritional care have expanded from survival and mimicking fetal growth to optimizing neurodevelopmental outcomes. Inadequate nutritional support may be a risk factor for major complications of prematurity; conversely, higher disease burden is a risk for growth restriction. Early complete parenteral nutrition support, including intr...

Early nutritional support for preterm infants is critical because such support influences long-term outcome. Minimal enteral feeding should be initiated as soon as possible if an infant is stable and if feeding advancement is recommended as relevant to the clinical course. Maternal milk is the gold standard for enteral feeding, but fortification may be needed to achieve optimal growth in a rapi...

Supplementation of certain micronutrients is recommended to ensure their adequate supply during pregnancy and lactation. In Germany, this applies particularly folic acid iodine. There no nationwide data on adherence the supplementation guidelines. The aim cross-sectional study was determine prevalence predictors both iodine in mothers a birth cohort. Data supplementation, before, during, shortl...

Children are unique as their food intake must provide sufficient nutrients not only for the maintenance of body tissues but also for growth. Improvements in techniques for nutritional support has resulted in very long term parenteral nutrition being available for those with chronic intestinal failure in addition to those who require short term parenteral feeding either following surgery or whil...

Obesity has origins extending to antenatal and early postnatal periods; however, the relationship between early postnatal diet and subsequent obesity is not well defined. The aims of this study were to determine whether early childhood dietary quality was associated with (a) infant and adolescent nutrition and (b) body mass index (BMI) in childhood and adolescence. The degree to which early nut...

Satisfactory nutrition of the low birth weight infant concerns the nurse, obstetrician, pediatrician, and nutritionist. It may be that at present the most satisfactory feeding for the low birth weight infants is human milk. Such factors as protein quantity and quality, fat quantity and quality, immune factors, and osmolar factors may be uniquely suitable for the human infant regardless of his w...

n BIOCHEMICAL, MOLECULAR, AND GENETIC MECHANISMS Methylselenol, a Selenium Metabolite, Induces Cell Cycle Arrest in G1 Phase and Apoptosis via the Extracellular-Regulated Kinase 1/2 Pathway and Other Cancer Signaling Genes Huawei Zeng, Min Wu, and James H. Botnen 1613 Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase ...

Nutrition of preterm infants should result in growth similar to that of normally growing fetuses of the same gestational age. Unfortunately, most preterm infants are not fed enough to achieve this objective; as a result they are growth restricted by term gestation. Recent studies have demonstrated that early and enhanced "aggressive" nutrition of preterm infants can reduce postnatal growth fail...

The human colonic microflora has a central role in health and disease, being unique in its complexity and range of functions. As such, dietary modulation is important for improved gut health, especially during the highly-sensitive stage of infancy. Diet can affect the composition of the gut microflora through the availability of different substrates for bacterial fermentation. Differences in gu...

Quality and safety aspects of infant nutrition are of key importance for child health, but oftentimes they do not get much attention by health care professionals whose interest tends to focus on functional benefits of early nutrition. Unbalanced diets and harmful food components induce particularly high risks for untoward effects in infants because of their rapid growth, high nutrient needs, an...