نتایج جستجو برای: infantile spasms

تعداد نتایج: 13984  

Journal: :Seizure 2005
S. Grosso D. Galimberti M. A. Farnetani M. Cioni R. Mostardini R. Vivarelli R. M. Di Bartolo E. Bernardoni R. Berardi G. Morgese P. Balestri

Studies of the efficacy of topiramate (TPM) in infants and young children are few. Here we report an open, prospective, and pragmatic study of effectiveness of TPM in terms of epilepsy syndromes, in children aged less than 2 years. The median follow-up period was 11 months. We enrolled 59 children in the study: 22 affected by localization-related epilepsy (LRE), 23 by generalized epilepsy, six ...

Journal: :AJNR. American journal of neuroradiology 1995
C W Shepherd O W Houser M R Gomez

PURPOSE To correlate the findings on MR scans of the brain in patients with tuberous sclerosis complex with mental disability and the type and age at onset of the first seizure. METHODS Patients with tuberous sclerosis complex who had MR brain scans were identified. The diagnosis was confirmed, and the clinical information on each patient was updated. The number, site, and area of abnormal si...

Journal: :Seizure 2014
Scott A. Burroughs Richard P. Morse Steven H. Mott Gregory L. Holmes

PURPOSE Hypsarrhythmia, the pathognomonic EEG pattern of West syndrome, is typically characterized by a high amplitude, arrhythmic, and asynchronous pattern. While this severely aberrant pattern would suggest severe abnormalities in connectivity, coherence has not yet been systematically assessed in hypsarrhythmia. METHODS We evaluated the EEGs of 28 infants, 12 with infantile spasms with hyp...

Journal: :Archives of disease in childhood 2005
H-S Wang M-F Kuo M-L Chou P-C Hung K-L Lin M-Y Hsieh M-Y Chang

AIM To study the difference between pyridoxine (PN) and its active form, pyridoxal phosphate, (PLP) in control of idiopathic intractable epilepsy in children. METHODS Among 574 children with active epilepsy, 94 (aged 8 months to 15 years) were diagnosed with idiopathic intractable epilepsy for more than six months. All received intravenous PLP 10 mg/kg, then 10 mg/kg/day in four divided doses...

Journal: :Neurobiology of disease 2010
Morris H Scantlebury Aristea S Galanopoulou Lenka Chudomelova Emmanuel Raffo David Betancourth Solomon L Moshé

Infantile spasms are characterized by age-specific expression of epileptic spasms and hypsarrhythmia and often result in significant cognitive impairment. Other epilepsies or autism often ensue especially in symptomatic IS (SIS). Cortical or subcortical damage, including white matter, have been implicated in the pathogenesis of SIS. To generate a model of SIS, we recreated this pathology by inj...

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