Antiseptic agents are increasingly used for hand hygiene and skin decolonization as key tools for the prevention of healthcare-associated infections. Chlorhexidine, a divalent, cationic biguanide, has a broad spectrum of activity and is one of the most frequently used topical antiseptic agents. Notably, there are an increasing number of prevalence studies that report reduced levels of susceptib...

Antiseptics and Disinfectants are widely used in hospitals and other health care centers to control the growth of microbes on both living tissues and inanimate objects. Different pathogens responded different antiseptics and disinfectants. Antibacterial effects of the antiseptics and disinfectants were also concentration dependent. Raut Gargi, Vanmali Harshad, Pimpliskar Mukesh

OBJECTIVES To incorporate behavioural insights into the user-centred design of an inpatient prescription chart (Imperial Drug Chart Evaluation and Adoption Study, IDEAS chart) and to determine whether changes in the content and design of prescription charts could influence prescribing behaviour and reduce prescribing errors. DESIGN A mixed-methods approach was taken in the development phase o...

From an ancient tool to a modern way of improving oral health, miswak (chewing stick) has proven to be an effective tool for oral health. The miswak removes the bacterial plaque by mechanical and chemical actions. It provides a cheap and easily accessible way of improving oral health of the individuals and populations. The use of miswak was promoted centuries ago by Prophet Muhammad (Peace be U...

I read with enthusiasm the manuscript by neurosurgeons Ren and Canavero on his progress toward the first human head transplantation procedure.[1] Certainly, history has demonstrated that many “quantum leaps” in medicine challenged the accepted norms at the time. However, I would suggest that no prior “quantum leap” in medicine (e.g., “antiseptic handwashing, balloon angioplasty”) compares to th...

OBJECTIVES The UK Department of Health has made recommendations on safe and appropriate prescribing of anti-infectives. In response, we reviewed our anti-infective policies to ensure they were in line with best practice. As a result, a new adult anti-infective policy was launched. To help facilitate its implementation, a quality improvement programme was established, with the aim of achieving >...

The Front Cover shows efforts among Brazilian, American, and European researchers to combat neglected tropical diseases. New heterocyclic compounds based on imidazopyridine/pyrimidine furopyridine cores originating from Brazil travel the USA Europe be developed as anti-infective agents against Trypanosomiases. By exploring chemical diversity at eight different positions of central core, we obta...