Current knowledge of the molecular basis of male infertility that is associated with oxidative stress, apoptosis, and chromatin damage calls for changes in the laboratory assessment of the fertility potential of semen samples.

Oxidative stress (OS) has been considered a major contributory factor to the infertility. Oxidative stress is the result of imbalance between the reactive oxygen species (ROS) and antioxidants in the body which can lead to sperm damage, deformity, and eventually male infertility. Although high concentrations of the ROS cause sperm pathology (ATP depletion) leading to insufficient axonemal phosp...

Oxidative stress occurs when the production of potentially destructive reactive oxygen species (ROS) exceeds the bodies own natural antioxidant defenses, resulting in cellular damage. Oxidative stress is a common pathology seen in approximately half of all infertile men. ROS, defined as including oxygen ions, free radicals and peroxides are generated by sperm and seminal leukocytes within semen...

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. The authors should be commended for their thorough review of DNA fragmentation and the clinical indications for testing. The basic science review of DNA fragmentation, oxidative stress, and its association with male infertility is detailed yet concise. The authors also present clinical scenarios to better illustrate t...

April 23–29 is National Infertility Awareness Week and is intended to increase awareness of infertility, which affects the reproductive systems of both women and men (1). In general, infertility is defined as the inability of couples to achieve pregnancy after ≥1 year of trying (1). However, given that fertility in women is known to decline steadily with age, some providers evaluate and treat w...

OBJECTIVES The emotional adjustment of couples undergoing assisted reproductive technology (ART) treatments has been widely studied; however, it remains unclear whether infertility history contributes to couples' adjustment. This study examined the impact of infertility history (duration of infertility and number of previous ART treatment cycles) on the emotional adjustment of couples undergoin...

Oxidative stress is one of the leading causes sperm dysfunction. Excessive amounts reactive oxygen species can damage membranes and disrupt their DNA integrity, which affects not only likelihood getting pregnant naturally, but also clinical outcomes assisted reproductive technologies risk miscarriage. Sperm cells are extremely vulnerable to oxidative stress, given limited functional reserve ant...

Abstract Background Infertility is a huge global problem with significant mental health burden. could become source of continuous stress leading to psychosocial issues including stress, anxiety, depression, and low self-esteem in these women. A cross-sectional, case-controlled study was conducted between January 2021 November the effect infertility on quality life. semi-structured questionnaire...

BACKGROUND Infertility all around the world and in every culture is recognized as a stressful and critical experience that threatens individual, familial, marital, and social stability. Thus, in accordance with the importance of a woman's mental health and the possible impact of mental health on treatment outcome, finding a way to deal with perceived stress in women can help improve pregnancy o...

BACKGROUND Infertility causes psychological and emotional tension in the couples and makes severe stress on infertile men and women. Relaxation technique is one of the methods that reduces the stress and can balance the human's emotions. This study aimed to determine the effect of relaxation on the infertile women's stress score. METHODS This was a semi-experimental and clinical trial study. ...