Adenomatous polyps are known precursor lesions for colorectal cancer and some hyperplastic polyps also have malignant potential. The use of aspirin and nonsteroidal anti-inflammatory drugs (NSAID) is associated with a reduced risk of adenomatous polyps; however, less evidence exists with regard to NSAID use and hyperplastic polyp risk. We conducted a colonoscopy-based case-control study includi...

BACKGROUND AND AIMS Ileosigmoid fistulas (ISFs) are frequently undiagnosed prior to surgery. This study was designed to describe a polyp or cluster of polyps limited to the sigmoid colon as a marker of ISF in patients with ileitis. This novel finding will increase a gastroenterologist's opportunity to detect them preoperatively and their prognostic implication of worsening ileitis. METHODS Th...

Background: Colonic polyps are the abnormal growths from colonic mucosa, usually benign but there is a definite though small risk for cancerous transformation. Scarce data about this condition available Northern India. In study we aimed to determine prevalence of in patients undergoing colonoscopy various health indications. addition, studied characteristics these including histological classif...

BACKGROUND Cap polyposis is a rarely encountered disease characterized by multiple distinctive inflammatory colonic polyps located from the rectum to the distal colon. The etiology of this disease is still unknown, and no specific treatment has been established. AIM We report three cases of cap polyposis that were cured following eradication therapy for Helicobacter pylori infection. METHOD...

CONTEXT Lymphatic vessels are believed to be absent in the colon above the level of the mucularis mucosae. However, in our experience, lymphatic vessels are sometimes identifiable within the lamina propria in the setting of inflammation and neoplasia. OBJECTIVE We sought to assess the presence of lymphatics within the colonic lamina propria in neoplastic and inflammatory conditions using the ...

UNLABELLED Glucocorticoids are considered the main treatment option for nasal polyps, but their effect is only recently being understood. AIM To evaluate whether fluticasone propionate (FP) inhibits the inflammatory process induced by TNF-alpha in vitro, and to assess if NF-kappaB is associated to this inhibition. STUDY DESIGN Experimental in vitro study. MATERIALS AND METHODS Nasal polyp...

BACKGROUND Leukotrienes, especially LTC4, are important inflammatory mediators in allergic and nonallergic inflammation of the entire airways. Of particular interest are numerous theories regarding the pathogenesis of aspirin intolerance with subsequent hyperproduction of leukotrienes and inhibition of cyclooxygenase. OBJECTIVE To examine the influence of the cysteinyl-leukotriene receptor an...