Citation: De Cicco P, Sanders T, Cirino G, Maloy KJ and Ianaro A (2018) Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis. Front. Immunol. 9:499. doi: 10.3389/fimmu.2018.00499 hydrogen sulfide reduces Myeloid-Derived suppressor cell-Mediated inflammatory response in a Model of Helicobacter hepaticus-induc...

Thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. The pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (CAMs) and promoting the secretion of inflammatory chemokines and cytokines. Dysregulated signaling functions of thro...

Alpha-melanocyte stimulating hormone (α-MSH) is involved in normal skin wound healing and also has anti-inflammatory properties. The association of α-MSH to polyelectrolyte layers with various supports has been shown to improve these anti-inflammatory properties. This study aimed to evaluate the effects of nanofibrous membrane functionalized with α-MSH linked to polyelectrolyte layers on gingiv...

In this paper we summarize the long-term effects of A-bomb radiation on the T-cell system and discuss the possible involvement of attenuated T-cell immunity in the disease development observed in A-bomb survivors. Our previous observations on such effects include impaired mitogen-dependent proliferation and IL-2 production, decreases in naive T-cell populations, and increased proportions of ane...

the important role of reperfusion therapies in the treatment of acute myocardial infarction is well documented. however, reperfusion therapies can initiate inflammatory response and may damage the myocardium. the purpose of current study was to compare the effects of percutaneous coronary intervention and thrombolytic therapy on inflammatory markers in the setting of st elevation myocardial inf...

introduction: astrocytes are the most abundant glial cell type. in addition to their neurological roles, astrocytes also have immune functions. they have been involved in antigen presentation in the central nervous system (cns). activated astrocytes express adhesion molecules, chemokines and release several inflammatory mediators, pro-inflammatory cytokines, neurotrophic and neuroprotective fac...

Coenzyme Q10 (CoQ10) has a number of important roles in the cell that are required for optimal functioning immune system. These include its essential role as an electron carrier mitochondrial respiratory chain, enabling process oxidative phosphorylation to occur with concomitant production ATP, together potential lipid-soluble antioxidant, protecting against free radical-induced oxidation. Furt...