objective(s) in recent years highly selective cox-2inhibitors were withdrawn from the market because of an increased risk of cardiovascular complications. in this study we were looking for potent compounds with moderate selectivity for cox-2. so, four analogues of 4, 5-diaryl-2-(2-alkylthio-5-imidazolyl) imidazole derivatives were synthesized and their anti-inflammatory and anti-nociceptive act...

OBJECTIVES Gonorrhoea is associated with adverse reproductive health outcomes, including pelvic inflammatory disease and increased HIV transmission. Our objective was to determine the association of demographic factors, sexual risk behaviours, and drug use with incident gonorrhoea reinfection among public STD clinic clients. METHODS A retrospective cohort study conducted from January 1994 thr...

introduction: it appears that some risk factors for coronary heart diseases (chd) initiate their influence in the childhood period and their clinical complications start to take effect in adulthood. it is possible that adolescent active or sedentary boys, have other inflammatory silent risk factors of chd, in addition to routine risk factors such as lipid profile. however, the scientific data a...