Previous studies have shown that deficiencies in visuospatial perception and semantic processing in people with Williams syndrome (WS) are due to deficient central cohesiveness. Unlike previous studies that used abstract stimuli, this study used pictures to determine the relative ability of people with WS to integrate contextual information with the aim of exploring the nature of central cohere...

Beat perception in music has been proposed to be a human universal that may have its origins in adaptive processes involving temporal entrainment such as social communication and interaction. We examined beat perception skills in individuals with Williams syndrome (WS), a genetic, neurodevelopmental disorder. Musical interest and hypersociability are two prominent aspects of the WS phenotype al...

In the last couple of years, the concept of a web service (WS) has emerged as an important paradigm for general application integration in the internet environment. More particularly, WS is viewed as an important vehicle for the creation of dynamic e-business applications and as a means for the J2EE and .NET worlds to come together. Several companies, including Microsoft, have been collaboratin...

Williams syndrome (WS) is associated with a distinct profile of relatively proficient skills within the verbal domain compared to the severe impairment of visuo-spatial processing. Abnormalities in executive functions and deficits in planning ability and spatial working memory have been described. However, to date little is known about the influence of executive function deficits on navigationa...

As ~75% of the Werner syndrome (WS) patients recognized between 1904 and 2008 all over the world are of Japanese origin, the most case reports and clinical studies on WS has been published in Japanese journals. Thus, the detailed English-written clinical review on the recent WS case reports has been warranted. Although WS has been characterized by a variety of clinical manifestations mimicking ...

Werner's syndrome (WS) is an inherited disease with clinical symptoms resembling premature aging. Early susceptibility to a number of major age-related diseases is a key feature of this disorder. The gene responsible for WS (known as WRN) was identified by positional cloning. The predicted protein is 1432 amino acids in length and shows significant similarity to DNA helicases. Four mutations in...

Introduction: Williams syndrome (WS) is a neurogenetic disorder associated with a mild to moderate cognitive impairment and a hypersocial personality, most notably an unusually high tendency to approach and interact with strangers (Järvinen-Pasley et al., 2008). Within the WS phenotype, increased sociability is accompanied by an interesting profile of music processing. Reports of increased emot...

Williams syndrome (WS) is a relatively rare multisystem neurodevelopmental disorder caused by a hemizygous deletion of contiguous genes on chromosome 7q11.23. Although WS does not predispose carriers to cancers, alterations of chromosome 7 are common in several human neoplasms. We report here a patient with WS and two different cancers, Burkitt lymphoma and Ewing sarcoma. Array-CGH analysis of ...

1 Main Theme of Thesis Web Services (WSs) are modular, self-describing, loosely-coupled, platform and programming language-agnostic software applications that can be advertised , located and used across the Internet. They are viewed as one of the promising technologies that could help business entities to automate their operations on the web on a large scale by automatic discovery and consumpti...